An RSI Understanding Risk method
Use of weight-of-evidence criteria
Use of weight-of-evidence criteria is one of the methods used by Risk Sciences International to better understand risk.
Broadly
Weight-of-evidence (WoE) approaches systematically integrate multiple sources and types of information to reach risk conclusions. This includes combining epidemiological, toxicological, mechanistic, and modeling data. WoE frameworks vary in formality but prioritize transparency, reproducibility, and logic in how evidence supports findings.
More specifically
RSI structures WoE assessments using clearly defined inclusion criteria, evidence grading, and decision logic. Whether evaluating carcinogenicity, endocrine activity, or behavioral responses, RSI documents how conclusions are drawn and uncertainties managed. This method strengthens the credibility and defensibility of RSI’s risk determinations across sectors.