RSI News

As necessary and sparingly, RSI publishes short news items that demonstrate the range of work in which our team is engaged. Only when relevant and permissible do we mention the actual client, otherwise we simply refer to the type of client.

Aging and cognitive decline

September 21, 2023

Working with the College of Physicians and Surgeons of Alberta, Risk Sciences International conducted a wide-ranging review of aging and cognitive decline, with specific focus on aging physicians and fitness to practice.  The publication in Aging & Mental Health documents domains of cognition that decline with older age, concerns with…

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Evidence-based Risk Assessment Framework

December 12, 2022

Working with international thought leaders in risk science, Risk Sciences International investigators contributed to the development of the evidenced-based risk assessment framework shown in the figure below.  The framework evolved from a workshop held at the University of Ottawa in December 2018, jointly organized by the McLaughlin Centre for Population Health Risk…

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Food safety assessments

November 17, 2022

Problem Formulation in Food Safety Assessments conducted by the European Food Safety Authority RSI investigators recently provided advise to the European Food Safety Authority (EFSA) on the problem formulation step in the EFSA scientific assessment approach shown in the figure below.  The recommended problem formulation framework is designed to translate the mandate into well-formulated assessment questions…

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Value of information analysis framework

October 28, 2022

In its 2007 report on Toxicity Testing in the 21st Century: A Vision and a Strategy, the US National Research Council  (NRC) highlighted need for more rapid toxicity testing strategies in order to expand the coverage of the large number of chemicals for which toxicological data is lacking. This need was further…

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Principles of risk decision-making

August 19, 2022

RSI investigators propose fundamental principles of risk decision-making, and explore their application in a range of real-world risk decision-making contexts. These ten principles will provide valuable guidance on addressing current and future risk issues facing civil societies worldwide.

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Risk of Myocarditis and Pericarditis

May 11, 2022

Using data from the US Centers for Disease Control (CDC) Vaccine Adverse Event Reporting System, RSI investigators collaborated on a study showing increased risks of myopericarditis – an inflammatory condition of the heart muscle – following mRNA COVID19 vaccination, with the highest risks seen in young males following a second…

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Quinolones and risk of retinal detachment

April 26, 2022

Following previous work on the potential risk of acute liver failure associated with quinolone antibiotics, RSI investigators, Mohamed Taher, Franco Momoli, Donald Mattison and Daniel Krewski evaluated the potential risk of retinal detachment (RD) associated with these medications. Although no cases of RD were linked to quinolones in clinical trials, some…

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IAI climate change report

April 12, 2022

The International Aluminium Institute (IAI) recently commissioned Climate Risk Institute (CRI) and Risk Sciences International (RSI) to produce a series of informational tools evaluating and explaining the future effects of climate change on the aluminium sector’s sustainability. A principle focus of the project was to highlight one of the most…

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Quinolones and risk of acute liver failure

April 12, 2022

Quinolones, are a class of widely used and popular powerful antibiotics with broad coverage. RSI investigators, Mohamed Taher, Franco Momoli, Donald Mattison and Daniel Krewski, recently published a series of three papers on investigating the risk of acute liver failure (ALF) following systemic administration of quinolones, based on a synthesis…

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