Understanding Risk
Understanding Risk
An RSI Understanding Risk method

Toxicological profiling

Toxicological profiling is one of the methods used by Risk Sciences International to better understand risk.

Broadly

Toxicological profiling characterizes the nature, potency, and mechanism of adverse effects associated with a substance. It integrates in vivo, in vitro, and in silico data to support hazard identification and dose-response assessment. The profile informs risk decisions across consumer safety, workplace, and environmental contexts.

More specifically

RSI compiles and interprets toxicological data for use in chemical registration, public health policy, and safety evaluation. Its experts apply structure-activity relationships, mechanistic data, and systematic review techniques. RSI ensures that toxicological profiles are current, transparent, and adapted to the specific decision context.

Methods for understanding, managing, and communicating risk