RSI Expert-Michael G Tyshenko

Michael G. Tyshenko

Senior Health Risk Analyst

Joined RSI in 2018

  • Accomplished research scientist in molecular and cellular biology

  • McLaughlin Chair recipient, University of Ottawa (5-year endowed position)

  • Interdisciplinary training in Public Health and Administration (Queen's University, MPA)

  • International health policy teaching experience in China and Latin America

  • Over 100 peer review publications, 12 book chapters and 2 books

Dr. Michael G. Tyshenko is a Senior Health Risk Analyst at Risk Sciences International (RSI), where he has contributed since 2018 to some of the organization’s most complex and cross-cutting public health risk projects. As RSI’s lead on chemical peer reviews, he brings extensive experience in regulatory science, biological risk, and science-policy integration to high-stakes evaluations that require both deep expertise and clear communication.

Dr. Tyshenko’s research and collaborations span pandemic preparedness, emerging infectious diseases, and global risk policy, with applied work on SARS, MERS, and COVID-19. His current projects include policy analysis for the World Health Organization’s Global Technical Strategy for Malaria 2016–2030, identifying barriers to malaria reduction targets in Sub-Saharan African countries; ongoing collaboration with Nepal’s Ministry of Health on mobile and e-health approaches for remote populations; and ecological climate modeling with partners in Egypt and Saudi Arabia to project how climate change may alter pest distributions affecting biodiversity and crop productivity—providing insights for adaptive management and agricultural resilience.

Drawing on more than two decades of experience at the intersection of risk science, epidemiology, and public health policy, Dr. Tyshenko is recognized for advancing interdisciplinary approaches to health risk evaluation and for bridging scientific evidence with actionable policy.

Pre-RSI

Dr. Tyshenko’s career has consistently bridged the life sciences, public health, and public administration. He holds a Ph.D. and M.Sc. in Biology from Queen’s University, completed postdoctoral training in Public Health at the University of Ottawa, and earned a second master’s degree—a Master of Public Administration—also from Queen’s. This rare combination of scientific and governance-focused training underpins his distinctive contributions to health risk analysis and policy engagement.

From 2009 to 2013, Dr. Tyshenko held the McLaughlin Chair in Biological Risk Assessment at the University of Ottawa, where he led both academic research and applied science-policy translation. During this time, he developed and delivered Johns Hopkins–style short courses in public health across China through a five-year collaborative university–government initiative, and completed a parallel two-year project in Costa Rica, partnering with local and national authorities to identify public health policy gaps and capacity needs.

His leadership extended to the digital realm as Scientific Director of Risk.com, a knowledge portal providing curated summaries of global health hazards. Over the course of his career, Dr. Tyshenko has authored more than 100 peer-reviewed articles, 12 book chapters, and two books—cementing his reputation as a versatile thinker capable of bridging scientific disciplines and policy environments.

Celebrating Nepal’s Constitution Day with Mr. Bhrigu Dhungana, Nepal’s ambassador to Canada. Our work on sustainability in Nepal resulted in the IUCN sponsored book, Sustainable Livelihood Systems in Nepal where I acted and the English copy editor and contributor. A second project involved needs assessments for expanding mountain tourism in Nepal. (Sept. 19, 2022).

Case studies associated with Michael G. Tyshenko

EFSA Framework for Problem Formulation

PROJECT DESCRIPTION

To enhance the methodological rigour of its scientific assessments, EFSA sought to develop a standardised framework for problem formulation (PF) within its non-application scientific assessment protocols. The goal was to support the planning phase of these assessments by establishing a...
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Expansion of the Stochastic Health Canada Quantitative Microbial Risk Assessment Tool

PROJECT DESCRIPTION

Health Canada sought to enhance its Quantitative Microbial Risk Assessment (QMRA) tool, originally developed over 15 years ago for stakeholders responsible for drinking water systems. With advancements in probabilistic modeling and microbial risk assessment, the client required updates to reflect...
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Measuring impact of zoonotic animal diseases in Canada

PROJECT DESCRIPTION

The Canadian Food Inspection Agency sought RSI’s support in exploring how human health impacts from zoonotic diseases could be compared consistently with other public health risks. Traditionally, animal disease control decisions relied on veterinary and economic measures, but there was...
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Finalization of Risk Assessment on Secure Opioid Dispensing Devices

PROJECT DESCRIPTION

To support decision-making around modifications to opioid agonist treatment delivery, a detailed risk assessment was requested to evaluate the integration of secure dispensing devices for direct patient access to hydromorphone. Building on a previously conducted preliminary assessment, the work required...
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External Peer Review of the Draft Screening Assessment Report on Selected C3-C5 Alcohols

PROJECT DESCRIPTION

To support the quality and defensibility of regulatory decision-making under the Canadian Environmental Protection Act, 1999 (CEPA), Health Canada engaged Risk Sciences International to coordinate an independent external peer review of the Draft Screening Assessment Report (DSAR) for Selected C3-C5...
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External Peer Consultation of the Inorganic – Late Biomonitoring Approach Draft Screening Assessment Report

PROJECT DESCRIPTION

To support the Chemicals Management Plan under the Canadian Environmental Protection Act (CEPA), Health Canada sought expert peer consultation for a draft screening assessment report (DSAR) evaluating 47 inorganic substances identified as priorities. The client required independent scientific and technical...
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Publications associated with Michael G. Tyshenko

A beta-helical antifreeze protein isoform with increased activity. Structural and functional insights.


ABSTRACT

The insect spruce budworm (Choristoneura fumiferana)(Cf) produces a number of isoforms of its highly active antifreeze protein (CfAFP). Although most of the CfAFP isoforms are in the 9-kDa range, isoforms containing a 30- or 31-amino acid insertion have also been...
Publication details about A beta-helical antifreeze protein isoform with increased activity. Structural and functional insights.

Principles of risk decision-making.


ABSTRACT

Risk management decisions in public health require consideration of a number of complex, often conflicting factors. The aim of this review was to propose a set of 10 fundamental principles to guide risk decision-making. Although each of these principles is...
Publication details about Principles of risk decision-making.

Using a stochastic continuous-time Markov chain model to examine alternative timing and duration of the COVID-19 lockdown in Kuwait: what can be done now?


ABSTRACT

BACKGROUND: Kuwait had its first COVID-19 in late February, and until October 6, 2020 it recorded 108,268 cases and 632 deaths. Despite implementing one of the strictest control measures-including a three-week complete lockdown, there was no sign of a declining...
Publication details about Using a stochastic continuous-time Markov chain model to examine alternative timing and duration of the COVID-19 lockdown in Kuwait: what can be done now?

Modeling the effect of lockdown timing as a COVID-19 control measure in countries with differing social contacts.


ABSTRACT

The application, timing, and duration of lockdown strategies during a pandemic remain poorly quantified with regards to expected public health outcomes. Previous projection models have reached conflicting conclusions about the effect of complete lockdowns on COVID-19 outcomes. We developed a...
Publication details about Modeling the effect of lockdown timing as a COVID-19 control measure in countries with differing social contacts.

Modeling the Impact of Climate Change on Cervid Chronic Wasting Disease in Semi-Arid South Texas.


ABSTRACT

Chronic wasting disease (CWD) is a spongiform encephalopathy disease caused by the transmission of infectious prion agents. CWD is a fatal disease that affects wild and farmed cervids in North America with few cases reported overseas. Social interaction of cervids,...
Publication details about Modeling the Impact of Climate Change on Cervid Chronic Wasting Disease in Semi-Arid South Texas.

Analysis of intervention effectiveness using early outbreak transmission dynamics to guide future pandemic management and decision-making in Kuwait.


ABSTRACT

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a World Health Organization designated pandemic that can result in severe symptoms and death that disproportionately affects older patients or those with comorbidities. Kuwait reported its first imported cases of COVID-19 on...
Publication details about Analysis of intervention effectiveness using early outbreak transmission dynamics to guide future pandemic management and decision-making in Kuwait.

Evaluation of the United States COVID-19 vaccine allocation strategy.


ABSTRACT

BACKGROUND: Anticipating an initial shortage of vaccines for COVID-19, the Centers for Disease Control (CDC) in the United States developed priority vaccine allocations for specific demographic groups in the population. This study evaluates the performance of the CDC vaccine allocation...
Publication details about Evaluation of the United States COVID-19 vaccine allocation strategy.

Mitigating the externality of diseases of poverty through health aid.


ABSTRACT

Externality exists in healthcare when an individual benefits from others being healthy as it reduces the probability of getting sick from illness. Healthy workers are considered to be the more productive labourers leading to a country's positive economic growth over...
Publication details about Mitigating the externality of diseases of poverty through health aid.

Toxicity testing in the 21st century: progress in the past decade and future perspectives.


ABSTRACT

Advances in the biological sciences have led to an ongoing paradigm shift in toxicity testing based on expanded application of high-throughput in vitro screening and in silico methods to assess potential health risks of environmental agents. This review examines progress...
Publication details about Toxicity testing in the 21st century: progress in the past decade and future perspectives.

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Expert editorials associated with Michael G. Tyshenko

Machine Learning and Risk Assessments – Are Humans Obsolete?

Human health risk assessment is a well-established methodology that identifies and quantifies the potential risk of adverse health effects in humans who may be exposed to chemical contaminants in environmental media, such as air, water, soil, and food (Fryer et al., 2006).  Human health risk assessments can extend to other areas...
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Outside RSI

Beyond his professional life, Dr. Tyshenko is a dedicated and accomplished triathlete, with over 100 Olympic-distance triathlons, multiple Half-Ironman races, and three Ironman completions to his name. He has represented Canada as an age-group athlete at the World Triathlon Championships in Deerhurst, later transitioning to longer endurance formats that echo the persistence and discipline he brings to his scientific work.

Dr. Tyshenko’s approach to public health is fundamentally holistic—integrating molecular biology, risk communication, ethics, and evidence-based policymaking. His athletic discipline, global perspective, and interdisciplinary fluency make him a valued contributor to RSI’s mission to understand, manage, and communicate health risks in a rapidly changing world.

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