Paul Price

Senior Analyst

PhD, MSc, BA, AA

Joined RSI in 2019

  • 45 years as a risk assessor

  • Senior scientist at The Dow Chemical Company and the American Petroleum Institute

  • Authored over 90 book chapters and papers

Personal introduction

In my 45 years of experience as an exposure and risk assessor, I have had the privilege of working with a diverse array of organizations, ranging from State and Federal governments to trade associations, large chemical manufacturers, and non-profit research organizations. Throughout my career, I've actively contributed to both national and international committees focused on assessing chemical risks.

During my tenure at the United States Environmental Protection Agency (EPA), I had the opportunity to serve in dual roles, as both a regulator and a research scientist. Additionally, I held the position of senior scientist at The Dow Chemical Company and the American Petroleum Institute. Notably, I co-founded The LifeLine Group, a nonprofit organization dedicated to producing publicly available software for assessing aggregate exposures to pesticides and industrial chemicals.

My commitment to advancing the field is reflected in my memberships in prestigious organizations such as the Society of Risk Analysis and the International Society for Exposure Science. I've also been a longstanding member of the Society of Toxicology.

Over the past fifteen years, my research has primarily focused on the intricacies of mixture risk assessments and how advancements in single chemical exposure and risk assessment methodologies can enhance our understanding of these complex scenarios.

I take pride in my extensive body of work, which includes the authorship of more than ninety papers and book chapters. These publications span a wide spectrum, encompassing pure and applied research, the utilization of scientific knowledge in regulatory affairs, and in-depth policy analysis. My research areas have encompassed the integration of mechanistic toxicity and exposure data into chemical risk assessments, as well as the identification of characteristic variations in aggregate and cumulative exposures originating from both near- and far-field sources, all achieved through the application of probabilistic models.

Throughout my career, I've delved into the assessment of solvents, industrial chemicals, pesticides, and chemicals found in consumer products. Recent publications have explored topics such as the application of value of information and cost-effectiveness techniques in selecting preferred toxicity tests, the development of an ontology for chemical interactions using the Adverse Outcome Pathway (AOP) framework, the utilization of agent-based models to predict long-term patterns in exposure-related human behaviors, and the investigation of whether the characteristics of single chemical exposures can serve as indicators of when mixtures pose potential concerns.

Paul's Current Focus at RSI

Dr. Paul Price is an exposure and risk assessor who has recently retired from the Office of Research and Development of the U.S. Environmental Protection Agency. He is an adjunct professor at the University of Iowa and a frequent guest lecturer. Dr. Price is active in the area of mixtures risk assessment. He is president of the Mixtures Specialty Section of the Society of Toxicology and has recently given a continuing education course on risks from combined exposures. Dr. Price serves on the European Food Safety Authority’s committee on risks from combined exposures. He was an invited speaker for the 2022 “ONE conference” in Brussels. Dr. Price is currently working on multiple publications on mixture risk assessment and the Mixture Adjustment Factor.

Paul's Works and Accomplishments


  • Society of Toxicology award for the outstanding paper in the field of biological modeling (2012 and 2019)
  • Society of Toxicology award for the outstanding paper in the field of risk assessment (1997 and 2016)
  • Society of Toxicology award for the best poster in the field of mixture toxicology (2017)
  • Society of Toxicology award for the best poster in the field of Risk Assessment toxicology (1996)
  • Society of Toxicology award for the top-ten poster in the field of risk assessment (1996, 2011, 2014, and 2016)
  • Society of Toxicology award for the top-five poster in the field of mixture toxicology (2016)
  • EPA Bronze Medal 1982
  • EPA Bronze Medal 1987
  • EPA Bronze Medal 2015

Federal and international committees

  • European Food Safety Authority, MIXTOX working group (ongoing). Provided comments and suggestions to EFSA on a guidance document “Guidance document on harmonised methodologies for human health, animal health and ecological risk assessment of combined exposure to multiple chemicals.” Currently working on definitions of assessment groups in mixture risk assessment.
  • EPA government liaison for the ILSI North America Food and Chemical Safety Committee (2018-2020). Identify emerging scientific issues and to recommend research programs to facilitate and promote food and chemical safety. Assist in establishing research priorities, evaluating proposals, and reviewing and critiquing manuscripts.
  • Organisation for Economic Co-operation and Development, Work group on cumulative exposures to chemicals (2015-2018). Part of EPA’s team for reviewing and commenting on the OECD project to create guidance on mixture risks.
  • American Chemistry Council, Long Range Research Initiative Board (2012-2014). Dow Chemical’s representative to board directing ten-million-dollar annual research fund.
  • ILSI-HESI workgroup on mixtures, synergy, use of the TTC. (2008-2010). Group performed major literature review of chemical synergy and develop an approach for using the TTC in mixture risk assessments as a tier 0 approach.
  • EPA-Army Corps of Engineers external peer review of the HARS risk assessment (2002-2003). This two-year appointment required a review of the human and ecological risks associated with the placement of remediation materials at the Historic Area Remediation Site (HARS) in New York Harbor.
  • EPA external peer review of RAGS guidance on the use of probabilistic models (2000) Served as chair of human health subcommittee of the external peer review panel for proposed guidance on the use of Monte Carlo modeling in the assessment of exposures at Superfund sites.
  • Member of State of California risk assessment advisory committee (1996-7). Exposure assessment subcommittee. Reviewed and prepared written comments on all interim and final reports.