Paul Price
Senior Analyst
PhD, MSc, BA, AA
Joined RSI in 2019
- 45 years as a risk assessor
- Senior scientist at The Dow Chemical Company and the American Petroleum Institute
- Authored over 90 book chapters and papers
Dr. Paul Price is a Senior Analyst at Risk Sciences International (RSI), bringing over four decades of experience as a pioneer in exposure science and chemical risk assessment. Since joining RSI in 2019, Dr. Price has focused on advancing mixture risk assessment—an increasingly vital area as regulators shift from assessing single chemicals in isolation to understanding the cumulative effects of combined exposures. His current work includes the development of Mixture Adjustment Factors, participation in international regulatory committees, and authorship of scholarly publications aimed at refining the science-policy interface of chemical mixture risk.
Dr. Price’s experience has made him a leading contributor to RSI’s scientific capabilities, particularly in projects that involve probabilistic modeling of exposures, application of mechanistic data in health risk evaluations, and translation of technical knowledge into usable tools and policy guidance for public agencies and industry stakeholders.
Pre-RSI
Dr. Price’s career spans a rare breadth of sectors—including government, industry, academia, and nonprofit science. He has held senior scientific roles at the U.S. Environmental Protection Agency, The Dow Chemical Company, and the American Petroleum Institute, and co‑founded The LifeLine Group, a nonprofit committed to public-access exposure modeling tools.
At the EPA, Dr. Price served in dual capacities as regulator and research scientist, contributing foundational work to probabilistic modeling methods and Monte Carlo approaches for site-based exposure assessments. He played key roles on numerous national and international panels, including the Organisation for Economic Co-operation and Development (OECD) and the International Life Sciences Institute (ILSI), where he helped shape emerging global standards for cumulative and aggregate exposure science.
His extensive publication record—over 90 peer-reviewed articles and book chapters—reflects a commitment to both applied and theoretical science. His research has addressed everything from value of information frameworks and agent-based behavioral exposure models, to the development of ontologies for chemical interactions using the Adverse Outcome Pathway (AOP) framework.
Case studies associated with Paul Price
Publications associated with Paul Price
Advancements in Life Cycle Human Exposure and Toxicity Characterization.
A Framework that Considers the Impacts of Time, Cost, and Uncertainty in the Determination of the Cost Effectiveness of Toxicity-Testing Methodologies.
A value of information framework for assessing the trade-offs associated with uncertainty, duration, and cost of chemical toxicity testing.
Using data on the uncertainty of LOAELs to model the probability of observing adverse effects in low-dose studies of the toxicity of chemical mixtures.
Assessing the impact of different assumptions on the size of a Mixture Assessment Factor (MAF) for chemical mixtures in surface waters using data from three recent monitoring studies.
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RSI News associated with Paul Price
Value of information
Use of Probabilistic Exposure Models in the Assessment of Dietary Exposure to Chemicals
Outside RSI
Dr. Price remains deeply engaged in the scientific community. He is currently President of the Mixtures Specialty Section of the Society of Toxicology, an adjunct professor at the University of Iowa, and a frequent lecturer on topics ranging from biological modeling to policy integration in exposure science. He serves on the European Food Safety Authority (EFSA) working group on combined chemical exposures, contributing to harmonized methodologies and assessment frameworks.
His many accolades include multiple awards from the Society of Toxicology, including for outstanding papers in biological modeling and risk assessment (1997, 2012, 2016, 2019), and multiple top poster awards across toxicology subfields. He has also been awarded the EPA Bronze Medal three times (1982, 1987, 2015) in recognition of his federal service contributions.
Whether working on risk from solvents and pesticides, or building decision frameworks to inform regulatory choice under uncertainty, Dr. Price has shaped the language, logic, and limits of exposure assessment as it is practiced today.
