C. Calvin Willhite
Dr. Willhite is an Associate Expert at Risk Sciences International, where he supports the development of quantitative health risk assessments for both naturally occurring and synthetic chemicals. His work draws on decades of experience integrating toxicological evidence, regulatory frameworks, and structure–activity data to inform science-based decision-making. His expertise adds significant value to RSI’s assessments of chemical tolerability, exposure limits, and public health protection standards.
Pre-RSI
Dr. Calvin Willhite is a highly respected toxicologist with decades of experience in developmental toxicology, chemical risk assessment, and quantitative structure–activity relationships (QSARs). Over the course of his distinguished career, he has advised a wide range of national and international scientific bodies on chemical safety and exposure guidelines.
Dr. Willhite has served on numerous high-profile expert committees, including the National Academy of Sciences’ Committee on Toxicology, the U.S. Environmental Protection Agency’s National Advisory Committee, and the Scientific Advisory Committee on Alternative Toxicological Methods (SACATM) of the National Toxicology Program. He has also contributed to the work of the International Life Sciences Institute (ILSI) through its Structure–Activity Database Project, and provided key insights to subcommittees of the National Research Council, notably those on submarine air quality and acute exposure guideline levels (AEGLs).
Further engagements include participation on the NSF Health Advisory Board, the American Conference of Governmental Industrial Hygienists (ACGIH) Committee on Threshold Limit Values, the International Agency for Research on Cancer (IARC) Cancer Chemoprevention Panel, and Cal/OSHA’s Lead in Construction PEL Committee—reflecting his broad influence on workplace and environmental health standards.
Publications associated with C. Calvin Willhite
The REACH registration process: A case study of metallic aluminium, aluminium oxide and aluminium hydroxide.
Association between aluminum in drinking water and incident Alzheimer’s disease in the Canadian Study of Health and Aging cohort.
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Outside RSI
Dr. Willhite is a long-standing member of the Society of Toxicology and a recognized authority in his field. His contributions have earned him inclusion in Who’s Who in America, Who’s Who in Science and Engineering, and Who’s Who in Medicine and Healthcare. He continues to provide thought leadership in the toxicological sciences and supports evidence-based policies through both peer-reviewed publications and expert committee service.
