Adverse effects of drugs among the elderly should be given special attention when considering a pharmacological intervention.
Two recent papers using large electronic health records have explored the impact of drugs with anticholinergic properties.
The first, “Associations between Anticholinergic Burden and Adverse Health Outcomes in Parkinson Disease” view here used a HealthFacts database (Cerner Corporation, Kansas City, Missouri, USA) composed of 16,302 patients with Parkinson disease.
The second “Anticholinergic drugs and risk of dementia: case-control study” view here utilized 14,453 patients with dementia and 86,403 controls from the UK Clinical Practice Research Datalink.
Both studies observed a robust relationship between the use of drugs with anticholinergic properties and adverse consequences, including dementia, increased risks of visit to emergency departments and risk of fracture. Both studies demonstrate the importance of large electronic health record systems in understanding adverse drug events.
Posted in RSI News
More RSI News
Dr. Donald R. Mattison co-authors: Adult Utilization of Psychiatric Drugs
Because there is limited information available concerning the use of psychiatric drugs among the US adult population, Drs Moore and Mattison sought to characterize adult…
Read News ItemRSI launches game-changing climate app
RSI launched the Climate Change Hazards Information Portal (CCHIP).
Read News ItemClimate change modelling for the Bow River watershed
Following up on the recommendations put forth by the Expert Management Panel on River Flood Mitigation, the Environmental and Safety Management (ESM) and Water Resources (WS)…
Read News ItemQuarterWatch analyzes MedWatch Reports
This issue of QuarterWatch analyzes MedWatch Reports from the third quarter of 2015. This issue identifies major differences in reports of cancer associated with drugs…
Read News Item