Following previous work on the potential risk of acute liver failure associated with quinolone antibiotics, RSI investigators, Mohamed Taher, Franco Momoli, Donald Mattison and Daniel Krewski evaluated the potential risk of retinal detachment (RD) associated with these medications.
Although no cases of RD were linked to quinolones in clinical trials, some reports of RD were noted in the US FDA Adverse Event Reporting System in conjunction with systemic use of quinolone antibiotics. Analysis of electronic health records from over 500 US healthcare institutions revealed elevated but non-significant risks in African Americans (ciprofloxacin and levofloxacin), those aged 56–70 years old (moxifloxacin), and women (ciprofloxacin).
The authors noted that these suggestions of increased risk observed in some population subgroups warrant further investigation.
Posted in RSI News
More RSI News
RSI receives National Defence funding
RSI is pleased to be the recipient of funding through the DND IDEaS COVID-19 Challenge. Under the supervision of Emma Hartnett, RSI will be developing…
Read News ItemWillhite receives prestigious SOT award
Calvin C. Willhite, an Associate Expert with Risk Sciences International working on a range of toxicological risk issues, was just announced as the recipient of the prestigious…
Read News ItemRSI gives keynote
RSI experts Jennifer Go and Daniel Krewski, were recently invited to present a paper on maternal and child environmental heath during a global, virtual workshop originating in Foshan, Guangdong, China.
Read News ItemRSI hosts Mitacs intern
Risk Sciences International will host Abdallah Alami as an intern in statistics with support from the Mitacs Accelerate program. This unique university-industry program supports interns at…
Read News Item