RSI assists organizations in achieving, auditing, or exceeding risk management standards through policy reviews, process design, and staff training. The firm emphasizes contextual adaptation, ensuring that compliance enhances—not replaces—organizational learning and decision quality. RSI’s expertise also supports internal culture change and capacity building.

In its 2007 report on Toxicity Testing in the 21st Century: A Vision and a Strategy, the US National Research Council  (NRC) highlighted need for more rapid toxicity testing strategies in order to expand the coverage of the large number of chemicals for which toxicological data is lacking. This need was further underscored by the NRC in…

Quinolones, are a class of widely used and popular powerful antibiotics with broad coverage. RSI investigators, Mohamed Taher, Franco Momoli, Donald Mattison and Daniel Krewski, recently published a series of three papers on investigating the risk of acute liver failure (ALF) following systemic administration of quinolones, based on a synthesis of evidence from available clinical…

RSI uses pathway mapping to support both qualitative and quantitative risk assessments. Whether mapping chemical exposure, behavioral change, or regulatory influence, RSI constructs clear, defensible diagrams and narratives. These help clients visualize risk processes and identify leverage points for mitigation or monitoring.

In high-risk or high-visibility environments, unclear or inaccessible communication undermines stakeholder confidence and can disrupt operations. Misinformation—or a lack of information—lowers trust, heightens scrutiny, and increases vulnerability to controversy and backlash. Effective communication meets both the sender’s and audience’s needs, strengthening credibility and trust. But message quality alone is not enough—targeted internal and external dissemination ensures it is heard.

RSI applies uncertainty propagation in its probabilistic risk models, supporting transparency and insight into the range and likelihood of possible results. RSI carefully documents input distributions, validates outputs, and interprets findings for decision contexts. The method helps RSI clients weigh risk-based decisions with a fuller appreciation of possible variation and confidence.

Calvin C. Willhite, an Associate Expert with Risk Sciences International working on a range of toxicological risk issues, was just announced as the recipient of the prestigious 2021 Arnold Lehman Award presented annually by the Society of Toxicology for outstanding contributions to evidence-based toxicology to improve public health. Dr. Willhite specializes in human health risk assessments for man-made…

RSI helps clients convey uncertainty in ways that are honest yet comprehensible. It uses visual tools, framing guidance, and scenario explanations to prevent misinterpretation. RSI supports regulators, scientists, and policymakers in maintaining credibility while addressing the real limits of knowledge and prediction in risk domains.

Dr. Donald Mattison, RSI’s Senior Vice-President and Chief Medical Officer, has accepted an appointment as a University of South Carolina Health Sciences Distinguished Professor in the in the Arnold School of Public Health (ASPH).  The appointment noted that Dr. Mattison’s broad and deep career experience as a researcher and educator is impressive and valuable to USC.  Dr Mattison’s academic…

RSI assists in aligning risk-related policies through structured gap analysis, stakeholder consultation, and systems mapping. Its cross-sectoral knowledge enables identification of misalignments and design of bridging mechanisms. RSI helps build governance structures that support harmonized policy implementation across diverse mandates.