Case Studies

The case studies listed here are for demonstration purposes exclusively. They are neither intended as references nor as validation by RSI clients. These case studies are a sample of the work done by RSI or directly led by its staff prior to joining RSI. They are intended as an illustration of the type of work that current RSI staff are able to deliver.

External Peer Review of the Draft Screening Assessment Report on Selected C3-C5 Alcohols

To support the quality and defensibility of regulatory decision-making under the Canadian Environmental Protection Act, 1999 (CEPA), Health Canada engaged Risk Sciences International to coordinate an independent external peer review of the Draft Screening Assessment Report (DSAR) for Selected C3-C5...
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Environmental Public Health Approach (EPHA) to Chemicals Expert Workshop

To advance the Government of Canada’s Chemicals Management Plan (CMP), a virtual expert workshop was planned and hosted to refine and evaluate a Canadian framework for the Environmental Public Health Approach (EPHA) to chemicals. The initiative focused on developing case...
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Communication material on lithium in drinking water and health risks

To support public communication around emerging drinking water concerns, RSI was engaged to develop accessible, scientifically grounded materials on lithium exposure and its potential health effects. The work focused on equipping stakeholders with clear, credible information that could inform both...
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Risk-Based Decision Making (RBDM) Compliance and Enforcement

Innovation, Science and Economic Development Canada (ISED), through its Spectrum Management Innovation Directorate, sought support in applying risk-based decision making (RBDM) across its compliance and enforcement responsibilities. The department was looking for a structured and data-driven approach to prioritize regulatory...
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Environmental Health Factors, Chronic Diseases, and Pandemic Resilience

To support more effective health policy and pandemic preparedness, this project examined how environmental health factors intersect with chronic disease and influence pandemic resilience. The client sought evidence to clarify how exposures to contaminants in air, water, and soil contribute...
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Risk Assessment of the Impact of Lethality Standards on Salmonellosis from Ready-to-Eat (RTE) Meat and Poultry Products

To support regulatory decision-making, a comprehensive risk assessment was conducted to evaluate how varying lethality performance standards would impact the public health burden of salmonellosis associated with Ready-to-Eat (RTE) meat and poultry products. The primary objective was to quantify the...
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Risk-Based Optimization of Enforcement Activities

A federal agency required scientific support to enhance the effectiveness of its environmental enforcement activities. This involved identifying and analyzing the risk factors—both environmental and human health-related—that contribute to the likelihood and impact of regulatory offences. The objective was to...
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Drinking Water Guidelines for Manganese

Establishing science-based drinking water guidelines for manganese requires integrating diverse regulatory approaches, emerging modeling tools, and evolving toxicological evidence. The client commissioned this project to systematically assess existing manganese drinking water guidelines and the scientific foundations upon which they are...
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Analysis in Support of Risk-Based Decision-Making for the Alberta Safety Codes Council

An independent regulatory organization responsible for oversight of Alberta’s safety codes system sought to strengthen its capacity for risk-based decision-making. The organization aimed to ensure that regulatory actions—particularly in the area of petroleum storage tanks—were guided by clear, evidence-based prioritization...
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Wildfire and residential smoke risk communication

Government authorities faced recurring challenges in communicating health risks from smoke caused by both wildfires and residential burning. While these events were becoming more frequent and more severe, the public health messages often failed to resonate with affected communities or...
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Canadian Recipient Hemovigilance System Renewal Consensus Conference

Following the planned closure of the Blood Safety Contribution Program (BSCP), support was needed to help define the structure, elements, and functions of a renewed national recipient hemovigilance system for Canada. The work centered on preparing the transfusion medicine community,...
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External Peer Consultation of the Inorganic – Late Biomonitoring Approach Draft Screening Assessment Report

To support the Chemicals Management Plan under the Canadian Environmental Protection Act (CEPA), Health Canada sought expert peer consultation for a draft screening assessment report (DSAR) evaluating 47 inorganic substances identified as priorities. The client required independent scientific and technical...
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Expansion of the Stochastic Health Canada Quantitative Microbial Risk Assessment Tool

Health Canada sought to enhance its Quantitative Microbial Risk Assessment (QMRA) tool, originally developed over 15 years ago for stakeholders responsible for drinking water systems. With advancements in probabilistic modeling and microbial risk assessment, the client required updates to reflect...
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Age-Related Cognitive Decline: Systematic Review and Meta-Analysis

The College of Physicians & Surgeons of Alberta (CPSA) commissioned a systematic review and meta-analysis to support evidence-informed decision-making around age-related cognitive decline among practicing physicians. The initiative was led by CPSA’s Physician Health Monitoring Program (PHMP), which sought to...
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