A Risk Sciences International Case Study

Risk Model Framework for Foodborne Campylobacteriosis via Poultry Meat Pathway

Campylobacteriosis via Poultry Meat Pathways

Client: Ministry for Primary Industries (New Zealand)

Listing of the client in no way affirms the client's support, sponsorship, or validation in any form of Risk Sciences International or the RSI staff member(s) who conducted this project during their stay with RSI or prior to joining the company. This case study is displayed for informative purposes only to demonstrate the capacity of RSI staff members. This case study reveals no proprietary information or information deemed sensitive.

Project description:

Risk Model Framework for Foodborne Campylobacteriosis via Poultry Meat Pathway

To support national public health goals, RSI was tasked with developing a quantitative microbiological risk assessment (QMRA) model to estimate the human health risks associated with the consumption of chicken in New Zealand. The core objective was to quantify the relationship between Campylobacter contamination on poultry carcasses at the point of chilling and the subsequent incidence of foodborne illness among consumers.

The work unfolded in two distinct phases. The first phase focused on evaluating the feasibility and practicality of such a model. This included a review of international and domestic risk assessment models for Campylobacter in chicken, an analysis of available data sources (including the National Microbiological Database), and the formulation of a pathway model structure. The proposed pathway accounted for multiple stages, including post-chill processing, retail handling, consumer practices (storage, handling, and cooking), and health outcomes. The model also integrated burden-of-illness estimates using Disability-Adjusted Life Years (DALYs), including acute illness and long-term sequelae such as Guillain-Barré syndrome.

Following a review checkpoint, the second phase involved developing the probabilistic risk assessment model itself. This model was built to be transparent, modifiable, and aligned with New Zealand-specific data where possible. It supported multiple simulation platforms and was designed to facilitate the testing of various assumptions, including alternative dose-response curves and regulatory targets. The model included capacity for sensitivity and uncertainty analysis to evaluate the impact of key parameters and explore the effects of policy changes on public health outcomes.

The resulting framework and model aimed to provide the analytical foundation needed to assess whether a proposed 20% reduction in campylobacteriosis could be achieved by modifying regulatory targets, particularly those relating to contamination levels post-chill.

Start: 2021

End: 2022

More RSI Case Studies

RSI presents a very small selection of case studies to highlight some of its key work.

Risk-Based Optimization of Enforcement Activities

A federal agency required scientific support to enhance the effectiveness of its environmental enforcement activities. This involved identifying and analyzing the risk factors—both environmental and human health-related—that contribute to the likelihood and impact of regulatory offences. The objective was to...
Read More about Risk-Based Optimization of Enforcement Activities

Environmental Health Factors, Chronic Diseases, and Pandemic Resilience

To support more effective health policy and pandemic preparedness, this project examined how environmental health factors intersect with chronic disease and influence pandemic resilience. The client sought evidence to clarify how exposures to contaminants in air, water, and soil contribute...
Read More about Environmental Health Factors, Chronic Diseases, and Pandemic Resilience

Systematic Review of Artificial Sweeteners and Health Risks

A comprehensive systematic review was undertaken to assess experimental evidence regarding the potential health risks associated with artificial sweeteners, specifically focusing on cancer and pre-term delivery. The client sought a rigorous analysis of both in vivo and in vitro experimental...
Read More about Systematic Review of Artificial Sweeteners and Health Risks

Finalization of Risk Assessment on Secure Opioid Dispensing Devices

To support decision-making around modifications to opioid agonist treatment delivery, a detailed risk assessment was requested to evaluate the integration of secure dispensing devices for direct patient access to hydromorphone. Building on a previously conducted preliminary assessment, the work required...
Read More about Finalization of Risk Assessment on Secure Opioid Dispensing Devices

Airport traffic flow and signage review

An international airport authority sought a comprehensive assessment of passenger and vehicle traffic flow after receiving complaints of confusion and safety concerns. Reports indicated that passengers were struggling to interpret signage, often stopping too long to process graphics, which caused...
Read More about Airport traffic flow and signage review

Risk Communication on McIntyre Powder

In response to increasing public concern about the historical use of McIntyre Powder—an aluminum-based substance once administered to miners in Ontario to prevent silicosis—the client sought expert guidance on managing risk communication related to potential health implications. Widespread media coverage...
Read More about Risk Communication on McIntyre Powder

Risk-Based Decision Making (RBDM) Compliance and Enforcement

Innovation, Science and Economic Development Canada (ISED), through its Spectrum Management Innovation Directorate, sought support in applying risk-based decision making (RBDM) across its compliance and enforcement responsibilities. The department was looking for a structured and data-driven approach to prioritize regulatory...
Read More about Risk-Based Decision Making (RBDM) Compliance and Enforcement

Communication material on lithium in drinking water and health risks

To support public communication around emerging drinking water concerns, RSI was engaged to develop accessible, scientifically grounded materials on lithium exposure and its potential health effects. The work focused on equipping stakeholders with clear, credible information that could inform both...
Read More about Communication material on lithium in drinking water and health risks

Environmental Public Health Approach (EPHA) to Chemicals Expert Workshop

To advance the Government of Canada’s Chemicals Management Plan (CMP), a virtual expert workshop was planned and hosted to refine and evaluate a Canadian framework for the Environmental Public Health Approach (EPHA) to chemicals. The initiative focused on developing case...
Read More about Environmental Public Health Approach (EPHA) to Chemicals Expert Workshop

Pickering Nuclear Facility Re‑licensing

The client sought support to finalize a Commission Member Document (CMD) for the re‑licensing of a nuclear facility. Recognizing the complexity and sensitivity of reactor re‑licensing, they requested assistance in crafting communication materials that were both technically comprehensive and accessible...
Read More about Pickering Nuclear Facility Re‑licensing

Age-Related Cognitive Decline: Systematic Review and Meta-Analysis

The College of Physicians & Surgeons of Alberta (CPSA) commissioned a systematic review and meta-analysis to support evidence-informed decision-making around age-related cognitive decline among practicing physicians. The initiative was led by CPSA’s Physician Health Monitoring Program (PHMP), which sought to...
Read More about Age-Related Cognitive Decline: Systematic Review and Meta-Analysis

Validation and Optimization of the Computational Tool for the Microbial Risk Assessment Framework (MRAF)

To support more consistent and quantitative assessments of new micro-organisms under the Canadian Environmental Protection Act, Health Canada's New Substances Program (NSP) sought to refine the tools and processes within its Microbial Risk Assessment Framework (MRAF). The NSP had previously...
Read More about Validation and Optimization of the Computational Tool for the Microbial Risk Assessment Framework (MRAF)

Assessing the Impact of Interstudy Variation in LOAELs on Findings of Low-Dose Additivity in In Vivo Studies of Mixtures

Demonstrating the safe use of chemical mixtures remains a critical challenge in toxicological science. In recent years, studies have suggested that chemicals can exhibit dose additivity—causing a combined effect—even when each chemical individually is below its effect threshold. This project...
Read More about Assessing the Impact of Interstudy Variation in LOAELs on Findings of Low-Dose Additivity in In Vivo Studies of Mixtures

Methodology for Developing Risk Significance Insights

The project centered on supporting the development of a methodology that could eventually be implemented as an Artificial Intelligence (AI) or Machine Learning (ML) process. The objective was to help formalize and potentially automate how professional judgment is applied when...
Read More about Methodology for Developing Risk Significance Insights

Update of WHO Guidance on Food Defense

To support international efforts in mitigating deliberate threats to the food system, the World Health Organization commissioned an update to its earlier guidance titled Terrorist Threats to Food. The revision aimed to broaden the original scope by addressing not only...
Read More about Update of WHO Guidance on Food Defense

Development of a National Food Safety Information System and Risk Assessment Capacity in Vietnam

Authorities in Vietnam sought targeted expertise to strengthen the country’s ability to detect, assess, and respond to food safety threats. This initiative had two linked objectives: building a comprehensive, transparent, and reliable national food safety information system, and enhancing risk...
Read More about Development of a National Food Safety Information System and Risk Assessment Capacity in Vietnam

Institutional & communications assessment

In the mid-1990s the International Organization for Migration (IOM) faced one of the most pivotal moments in its history. Though it counted 76 member states, it remained outside the United Nations system, and its work was increasingly perceived to overlap...
Read More about Institutional & communications assessment