A Risk Sciences International Case Study

Expansion of the Stochastic Health Canada Quantitative Microbial Risk Assessment Tool

Drinking water

Client: Health Canada

Listing of the client in no way affirms the client's support, sponsorship, or validation in any form of Risk Sciences International or the RSI staff member(s) who conducted this project during their stay with RSI or prior to joining the company. This case study is displayed for informative purposes only to demonstrate the capacity of RSI staff members. This case study reveals no proprietary information or information deemed sensitive.

Project description:

Expansion of the Stochastic Health Canada Quantitative Microbial Risk Assessment Tool

Health Canada sought to enhance its Quantitative Microbial Risk Assessment (QMRA) tool, originally developed over 15 years ago for stakeholders responsible for drinking water systems. With advancements in probabilistic modeling and microbial risk assessment, the client required updates to reflect current scientific standards and practices. Specifically, the project aimed to incorporate a "reverse QMRA" capability, allowing users to back-calculate from acceptable risk thresholds to necessary treatment interventions or source water quality targets.

To support this expansion, the project began with a focused review of how reverse QMRA methods are currently used in microbial risk modeling. Building on those insights, RSI developed new analytical components that allow the tool to work backward from health risk thresholds to identify required treatment levels or acceptable source water concentrations. This involved writing new core code and refining the interface to accommodate added flexibility and usability for different analytical scenarios.

The updated tool allows stakeholders to explore what levels of treatment are necessary to meet tolerable health risk thresholds under various source water conditions. This capability supports informed decision-making by facility operators working toward compliance with Health Canada’s drinking water guidelines. RSI was also responsible for testing the tool with feedback from Health Canada, updating technical documentation, and delivering both a summary presentation and a draft publication outlining the expanded methodology. The project was designed to result in an open-access, user-friendly application suitable for broad public use.

Start: 2024

Experts related to this case study

Emma Hartnett

Vice-President Risk Modelling and Simulation

Dr. Emma Hartnett is Vice-President, Risk Modelling and Simulation at Risk Sciences International (RSI), where she has been a foundational member since its inception in 2006. A globally recognized authority in quantitative risk assessment (QRA), she specializes in developing risk...
Read More about Emma Hartnett

Margaret Wilson

Senior Risk Analyst

Margaret Wilson is a Senior Risk Analyst at Risk Sciences International (RSI), where she has been a foundational member since the company’s inception in 2006. Drawing on a rare combination of scientific breadth and analytical precision, Margaret has supported and...
Read More about Margaret Wilson

Michael G. Tyshenko

Senior Health Risk Analyst

Dr. Michael G. Tyshenko is a Senior Health Risk Analyst at Risk Sciences International (RSI), where he has contributed since 2018 to the organization’s most complex and cross-cutting public health risk issues. As RSI’s lead on chemical peer reviews, he...
Read More about Michael G. Tyshenko

More RSI Case Studies

RSI presents a very small selection of case studies to highlight some of its key work.

Update of WHO Guidance on Food Defense

To support international efforts in mitigating deliberate threats to the food system, the World Health Organization commissioned an update to its earlier guidance titled Terrorist Threats to Food. The revision aimed to broaden the original scope by addressing not only...
Read More about Update of WHO Guidance on Food Defense

Validation and Optimization of the Computational Tool for the Microbial Risk Assessment Framework (MRAF)

To support more consistent and quantitative assessments of new micro-organisms under the Canadian Environmental Protection Act, Health Canada's New Substances Program (NSP) sought to refine the tools and processes within its Microbial Risk Assessment Framework (MRAF). The NSP had previously...
Read More about Validation and Optimization of the Computational Tool for the Microbial Risk Assessment Framework (MRAF)

EFSA Framework for Problem Formulation

To enhance the methodological rigour of its scientific assessments, EFSA sought to develop a standardised framework for problem formulation (PF) within its non-application scientific assessment protocols. The goal was to support the planning phase of these assessments by establishing a...
Read More about EFSA Framework for Problem Formulation

Wildfire and residential smoke risk communication

Government authorities faced recurring challenges in communicating health risks from smoke caused by both wildfires and residential burning. While these events were becoming more frequent and more severe, the public health messages often failed to resonate with affected communities or...
Read More about Wildfire and residential smoke risk communication

Development of a National Food Safety Information System and Risk Assessment Capacity in Vietnam

Authorities in Vietnam sought targeted expertise to strengthen the country’s ability to detect, assess, and respond to food safety threats. This initiative had two linked objectives: building a comprehensive, transparent, and reliable national food safety information system, and enhancing risk...
Read More about Development of a National Food Safety Information System and Risk Assessment Capacity in Vietnam