A Risk Sciences International Case Study

Environmental Health Factors, Chronic Diseases, and Pandemic Resilience

Environmental health factors

Client: Health Canada

Listing of the client in no way affirms the client's support, sponsorship, or validation in any form of Risk Sciences International or the RSI staff member(s) who conducted this project during their stay with RSI or prior to joining the company. This case study is displayed for informative purposes only to demonstrate the capacity of RSI staff members. This case study reveals no proprietary information or information deemed sensitive.

Project description:

Environmental Health Factors, Chronic Diseases, and Pandemic Resilience

To support more effective health policy and pandemic preparedness, this project examined how environmental health factors intersect with chronic disease and influence pandemic resilience. The client sought evidence to clarify how exposures to contaminants in air, water, and soil contribute to the environmental burden of disease in Canada and exacerbate vulnerability to infectious disease outcomes, including COVID-19.

The objective was to consolidate scientific evidence on the health impacts of environmental determinants—such as chemical exposures and poor environmental quality—and how these may increase susceptibility to diseases like COVID-19, especially among marginalized populations. The client also aimed to explore how these environmental factors relate to long-term health resilience and to identify actionable strategies for recovery and prevention in future public health crises.

Work involved a rapid scoping review of literature from the past two decades, emphasizing evidence relevant to Canada while allowing for contextual insights from jurisdictions like the US, EU, and Australia. The review addressed several key questions: the current environmental burden of disease; the role of comorbidities in susceptibility to SARS-CoV-2; strategies for reducing environmental risk over time; integration of environmental determinants into population health approaches; and the compounding impact of social inequities.

The final output was a comprehensive report structured around these questions, supported by a high-level summary document featuring graphical elements to improve readability. The project was designed to support Health Canada’s efforts to prioritize and implement environmental health actions that promote recovery and build long-term resilience in Canada’s public health systems.

Start: 2021

End: 2021

Experts related to this case study

Franco Momoli

Vice-President Chemical and Product Safety

Dr. Franco Momoli joined Risk Sciences International (RSI) in 2019 and currently serves as Vice-President, Chemical and Product Safety. In this role, he leads a multidisciplinary team of epidemiologists, risk assessors, toxicologists, and biostatisticians in conducting human health risk assessments...
Read More about Franco Momoli

More RSI Case Studies

RSI presents a very small selection of case studies to highlight some of its key work.

Drinking Water Guidelines for Manganese

Establishing science-based drinking water guidelines for manganese requires integrating diverse regulatory approaches, emerging modeling tools, and evolving toxicological evidence. The client commissioned this project to systematically assess existing manganese drinking water guidelines and the scientific foundations upon which they are...
Read More about Drinking Water Guidelines for Manganese

Systematic Review of Artificial Sweeteners and Health Risks

A comprehensive systematic review was undertaken to assess experimental evidence regarding the potential health risks associated with artificial sweeteners, specifically focusing on cancer and pre-term delivery. The client sought a rigorous analysis of both in vivo and in vitro experimental...
Read More about Systematic Review of Artificial Sweeteners and Health Risks

Airport traffic flow and signage review

An international airport authority sought a comprehensive assessment of passenger and vehicle traffic flow after receiving complaints of confusion and safety concerns. Reports indicated that passengers were struggling to interpret signage, often stopping too long to process graphics, which caused...
Read More about Airport traffic flow and signage review

Technical Support for Risk-Based Decision Making (RBDM)

To enhance the oversight of cannabis production under its regulatory mandate, the Cannabis Directorate sought expert support in developing a risk-based decision-making framework tailored to its compliance and enforcement responsibilities. The directorate aimed to better assess and respond to non-conformance...
Read More about Technical Support for Risk-Based Decision Making (RBDM)

Wildfire and residential smoke risk communication

Government authorities faced recurring challenges in communicating health risks from smoke caused by both wildfires and residential burning. While these events were becoming more frequent and more severe, the public health messages often failed to resonate with affected communities or...
Read More about Wildfire and residential smoke risk communication

External Peer Review of the Draft Screening Assessment Report on Selected C3-C5 Alcohols

To support the quality and defensibility of regulatory decision-making under the Canadian Environmental Protection Act, 1999 (CEPA), Health Canada engaged Risk Sciences International to coordinate an independent external peer review of the Draft Screening Assessment Report (DSAR) for Selected C3-C5...
Read More about External Peer Review of the Draft Screening Assessment Report on Selected C3-C5 Alcohols

Risk-based decision making framework

The Alliance of Blood Operators (ABO) sought to move its members toward a consistent, transparent approach to risk-based decision-making. Having worked through the development of a framework, the organization now wanted formal adoption, external validation, and practical application to real-world...
Read More about Risk-based decision making framework

Risk Assessment of the Impact of Lethality Standards on Salmonellosis from Ready-to-Eat (RTE) Meat and Poultry Products

To support regulatory decision-making, a comprehensive risk assessment was conducted to evaluate how varying lethality performance standards would impact the public health burden of salmonellosis associated with Ready-to-Eat (RTE) meat and poultry products. The primary objective was to quantify the...
Read More about Risk Assessment of the Impact of Lethality Standards on Salmonellosis from Ready-to-Eat (RTE) Meat and Poultry Products

Applying New Assessment Methods (NAMs) for Assessing Semi-Volatile Organic Compounds (SVOCs) in Indoor Residential Environments

Health Canada sought expert support in advancing its efforts to develop screening values for semi-volatile organic compounds (SVOCs) commonly found in residential indoor environments. Previous work on indoor air contaminants had focused on volatile organic compounds (VOCs), where screening values...
Read More about Applying New Assessment Methods (NAMs) for Assessing Semi-Volatile Organic Compounds (SVOCs) in Indoor Residential Environments

Canadian Recipient Hemovigilance System Renewal Consensus Conference

Following the planned closure of the Blood Safety Contribution Program (BSCP), support was needed to help define the structure, elements, and functions of a renewed national recipient hemovigilance system for Canada. The work centered on preparing the transfusion medicine community,...
Read More about Canadian Recipient Hemovigilance System Renewal Consensus Conference

Risk-Based Decision Making (RBDM) Compliance and Enforcement

Innovation, Science and Economic Development Canada (ISED), through its Spectrum Management Innovation Directorate, sought support in applying risk-based decision making (RBDM) across its compliance and enforcement responsibilities. The department was looking for a structured and data-driven approach to prioritize regulatory...
Read More about Risk-Based Decision Making (RBDM) Compliance and Enforcement

Update of WHO Guidance on Food Defense

To support international efforts in mitigating deliberate threats to the food system, the World Health Organization commissioned an update to its earlier guidance titled Terrorist Threats to Food. The revision aimed to broaden the original scope by addressing not only...
Read More about Update of WHO Guidance on Food Defense

Development of a National Food Safety Information System and Risk Assessment Capacity in Vietnam

Authorities in Vietnam sought targeted expertise to strengthen the country’s ability to detect, assess, and respond to food safety threats. This initiative had two linked objectives: building a comprehensive, transparent, and reliable national food safety information system, and enhancing risk...
Read More about Development of a National Food Safety Information System and Risk Assessment Capacity in Vietnam

EFSA Framework for Problem Formulation

To enhance the methodological rigour of its scientific assessments, EFSA sought to develop a standardised framework for problem formulation (PF) within its non-application scientific assessment protocols. The goal was to support the planning phase of these assessments by establishing a...
Read More about EFSA Framework for Problem Formulation

Institutional & communications assessment

In the mid-1990s the International Organization for Migration (IOM) faced one of the most pivotal moments in its history. Though it counted 76 member states, it remained outside the United Nations system, and its work was increasingly perceived to overlap...
Read More about Institutional & communications assessment

Risk Model Framework for Foodborne Campylobacteriosis via Poultry Meat Pathway

To support national public health goals, RSI was tasked with developing a quantitative microbiological risk assessment (QMRA) model to estimate the human health risks associated with the consumption of chicken in New Zealand. The core objective was to quantify the...
Read More about Risk Model Framework for Foodborne Campylobacteriosis via Poultry Meat Pathway

Evaluation of Drug Recall Communication and Risk Determination Processes

In response to public and ministerial concerns about the timeliness and adequacy of information shared during a major prescription drug recall, Health Canada commissioned an independent review to assess its response to the event. The situation involved a recall of...
Read More about Evaluation of Drug Recall Communication and Risk Determination Processes

Developing a Risk-Based Compliance Framework for Digital Service Delivery

The Financial Consumer Agency of Canada (FCAC) engaged Risk Sciences International to provide strategic advisory services aimed at enhancing its regulatory compliance model through risk-based methodologies. FCAC’s objective was to explore new approaches that would integrate digital tools and data-driven...
Read More about Developing a Risk-Based Compliance Framework for Digital Service Delivery