Publication related to RSI or an RSI staff member
Back to publications list

Effectiveness of personal protective measures in reducing pandemic influenza transmission: A systematic review and meta-analysis.

The goal of this review was to examine the effectiveness of personal protective measures in preventing pandemic influenza transmission in human populations. We collected primary studies from Medline, Embase, PubMed, Cochrane Library, CINAHL and grey literature. Where appropriate, random effects meta-analyses were conducted using inverse variance statistical calculations. Meta-analyses suggest that regular hand hygiene provided a significant protective effect (OR=0.62; 95% CI 0.52-0.73; I(2)=0%), and facemask use provided a non-significant protective effect (OR=0.53; 95% CI 0.16-1.71; I(2)=48%) against 2009 pandemic influenza infection. These interventions may therefore be effective at limiting transmission during future pandemics. PROSPERO Registration: 42016039896.

Authors

  • Saunders-Hastings, Patrick, Saunders-Hastings P, University of Ottawa, McLaughlin Centre for Population Health Risk Assessment, 850 Peter Morand Crescent, Ottawa, ON, K1G 5Z3, Canada. Electronic address: psaun076@uottawa.ca.

  • Crispo, James A G, Crispo JAG, University of Ottawa, McLaughlin Centre for Population Health Risk Assessment, 850 Peter Morand Crescent, Ottawa, ON, K1G 5Z3, Canada; University of Pennsylvania, Department of Neurology, Philadelphia, PA, United States.

  • Sikora, Lindsey, Sikora L, University of Ottawa, Health Sciences Library,451 Smyth Road, Ottawa, ON, Canada.

  • Krewski, Daniel, Krewski D, University of Ottawa, McLaughlin Centre for Population Health Risk Assessment, 850 Peter Morand Crescent, Ottawa, ON, K1G 5Z3, Canada.

YEAR OF PUBLICATION: 2017
SOURCE: Epidemics. 2017 Sep;20:1-20. doi: 10.1016/j.epidem.2017.04.003. Epub 2017 Apr 30.
JOURNAL TITLE ABBREVIATION: Epidemics
JOURNAL TITLE: Epidemics
ISSN: 1878-0067 (Electronic) 1878-0067 (Linking)
VOLUME: 20
PAGES: 1-20
PLACE OF PUBLICATION: Netherlands
ABSTRACT:
The goal of this review was to examine the effectiveness of personal protective measures in preventing pandemic influenza transmission in human populations. We collected primary studies from Medline, Embase, PubMed, Cochrane Library, CINAHL and grey literature. Where appropriate, random effects meta-analyses were conducted using inverse variance statistical calculations. Meta-analyses suggest that regular hand hygiene provided a significant protective effect (OR=0.62; 95% CI 0.52-0.73; I(2)=0%), and facemask use provided a non-significant protective effect (OR=0.53; 95% CI 0.16-1.71; I(2)=48%) against 2009 pandemic influenza infection. These interventions may therefore be effective at limiting transmission during future pandemics. PROSPERO Registration: 42016039896.
COPYRIGHT INFORMATION: Copyright (c) 2017 The Authors. Published by Elsevier B.V. All rights reserved.
LANGUAGE: eng
DATE OF PUBLICATION: 2017 Sep
DATE OF ELECTRONIC PUBLICATION: 20170430
DATE COMPLETED: 20180917
DATE REVISED: 20250623
MESH DATE: 2018/09/18 06:00
EDAT: 2017/05/11 06:00
STATUS: MEDLINE
PUBLICATION STATUS: ppublish
LOCATION IDENTIFIER: S1755-4365(16)30085-8 [pii] 10.1016/j.epidem.2017.04.003 [doi]
OWNER: NLM

Related RSI Experts

Daniel Krewski

Chief Risk Scientist
Dr. Daniel Krewski is Chief Risk Scientist and co-founder of Risk Sciences International (RSI), a firm established in 2006 to bring evidence-based, multidisciplinary expertise to the challenge of understanding, managing, and communicating risk. As RSI’s inaugural CEO and long-time scientific...
Read More about Daniel Krewski