Publication related to RSI or an RSI staff member

Blood transfusion and hemostatic agents used during radical cystectomy.

BACKGROUND: Radical cystectomy may result in significant blood loss necessitating transfusion. The purpose of this study was to determine what intra-operative techniques and hemostatic agents are currently used by uro-oncologists to prevent and control blood loss during radical cystectomy. METHODS: In August 2011, members of the Society of Urologic Oncology (SUO) were solicited to complete an online survey. Residents, fellows and non-urologists were excluded. Canadian members received a personal email invitation. Respondents were asked to provide demographic information and opinions regarding blood loss and transfusion. Participants were also asked to report techniques used to reduce blood loss. RESULTS: Of the 34 Canadian SUO members with registered email addresses, 27 (79%) completed the survey and met inclusion criteria as staff urologists who perform radical cystectomy. In addition, 52 non-Canadian SUO members were included in the analysis. Among all SUO respondents, a high proportion (73; 88%) reported using topical hemostatic agents during cystectomy. Thirty-six (46%) surgeons reported occasionally using procedural techniques and 9 (11%) using systemic hemostatic agents. Number of years since training was associated with decreased use of topical agents and increased use of procedural techniques (p < 0.01). Number of cystectomies per year was associated with decreased use of topical hemostatic agents (p < 0.01). INTERPRETATION: Based on a survey of practice, there is significant risk of blood loss requiring transfusion during radical cystectomy. Surgeons frequently use topical hemostatic agents and rarely use systemic drugs to prevent or control blood loss. Trials evaluating agents and techniques to reduce blood loss during radical cystectomy are needed.

Authors

  • Punjani, Nahid, Punjani N, University of Ottawa Medical School, University of Ottawa, Ottawa, ON;

  • Lavallee, Luke T, Lavallee LT,

  • Momoli, Franco, Momoli F,

  • Fergusson, Dean, Fergusson D,

  • Witiuk, Kelsey, Witiuk K,

  • Mallick, Ranjeeta, Mallick R,

  • Morash, Christopher, Morash C,

  • Cagiannos, Ilias, Cagiannos I,

  • Breau, Rodney H, Breau RH,

YEAR OF PUBLICATION: 2013
SOURCE: Can Urol Assoc J. 2013 May-Jun;7(5-6):E275-80. doi: 10.5489/cuaj.1002.
JOURNAL TITLE ABBREVIATION: Can Urol Assoc J
JOURNAL TITLE: Canadian Urological Association journal = Journal de l'Association des urologues du Canada
ISSN: 1911-6470 (Print) 1920-1214 (Electronic) 1911-6470 (Linking)
VOLUME: 7
ISSUE: 5-6
PAGES: E275-80
PLACE OF PUBLICATION: Canada
ABSTRACT:
BACKGROUND: Radical cystectomy may result in significant blood loss necessitating transfusion. The purpose of this study was to determine what intra-operative techniques and hemostatic agents are currently used by uro-oncologists to prevent and control blood loss during radical cystectomy. METHODS: In August 2011, members of the Society of Urologic Oncology (SUO) were solicited to complete an online survey. Residents, fellows and non-urologists were excluded. Canadian members received a personal email invitation. Respondents were asked to provide demographic information and opinions regarding blood loss and transfusion. Participants were also asked to report techniques used to reduce blood loss. RESULTS: Of the 34 Canadian SUO members with registered email addresses, 27 (79%) completed the survey and met inclusion criteria as staff urologists who perform radical cystectomy. In addition, 52 non-Canadian SUO members were included in the analysis. Among all SUO respondents, a high proportion (73; 88%) reported using topical hemostatic agents during cystectomy. Thirty-six (46%) surgeons reported occasionally using procedural techniques and 9 (11%) using systemic hemostatic agents. Number of years since training was associated with decreased use of topical agents and increased use of procedural techniques (p < 0.01). Number of cystectomies per year was associated with decreased use of topical hemostatic agents (p < 0.01). INTERPRETATION: Based on a survey of practice, there is significant risk of blood loss requiring transfusion during radical cystectomy. Surgeons frequently use topical hemostatic agents and rarely use systemic drugs to prevent or control blood loss. Trials evaluating agents and techniques to reduce blood loss during radical cystectomy are needed.
LANGUAGE: eng
DATE OF PUBLICATION: 2013 May-Jun
DATE COMPLETED: 20130617
DATE REVISED: 20240607
MESH DATE: 2013/06/15 06:01
EDAT: 2013/06/15 06:00
STATUS: PubMed-not-MEDLINE
PUBLICATION STATUS: ppublish
LOCATION IDENTIFIER: 10.5489/cuaj.1002 [doi]
OWNER: NLM

Related RSI Experts

Franco Momoli

Vice-President Chemical and Product Safety

Dr. Franco Momoli joined Risk Sciences International (RSI) in 2019 and currently serves as Vice-President, Chemical and Product Safety. In this role, he leads a multidisciplinary team of epidemiologists, risk assessors, toxicologists, and biostatisticians in conducting human health risk assessments...
Read More about Franco Momoli