Publication related to RSI or an RSI staff member
A risk-based classification scheme for genetically modified foods. III: Evaluation using a panel of reference foods.
Authors
- Chao, Eunice, Chao E, McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, 1 Stewart Street, Ottawa, Ont., Canada K1N 6N5. echao@uottawa.ca
- Krewski, Daniel, Krewski D,
YEAR OF PUBLICATION: 2008
SOURCE: Regul Toxicol Pharmacol. 2008 Dec;52(3):235-41. doi: 10.1016/j.yrtph.2008.08.003. Epub 2008 Aug 15.
JOURNAL TITLE ABBREVIATION: Regul Toxicol Pharmacol
JOURNAL TITLE: Regulatory toxicology and pharmacology : RTP
ISSN: 1096-0295 (Electronic) 0273-2300 (Linking)
VOLUME: 52
ISSUE: 3
PAGES: 235-41
PLACE OF PUBLICATION: Netherlands
ABSTRACT:
This paper presents an exploratory evaluation of four functional components of a proposed risk-based classification scheme (RBCS) for crop-derived genetically modified (GM) foods in a concordance study. Two independent raters assigned concern levels to 20 reference GM foods using a rating form based on the proposed RBCS. The four components of evaluation were: (1) degree of concordance, (2) distribution across concern levels, (3) discriminating ability of the scheme, and (4) ease of use. At least one of the 20 reference foods was assigned to each of the possible concern levels, demonstrating the ability of the scheme to identify GM foods of different concern with respect to potential health risk. There was reasonably good concordance between the two raters for the three separate parts of the RBCS. The raters agreed that the criteria in the scheme were sufficiently clear in discriminating reference foods into different concern levels, and that with some experience, the scheme was reasonably easy to use. Specific issues and suggestions for improvements identified in the concordance study are discussed.
This paper presents an exploratory evaluation of four functional components of a proposed risk-based classification scheme (RBCS) for crop-derived genetically modified (GM) foods in a concordance study. Two independent raters assigned concern levels to 20 reference GM foods using a rating form based on the proposed RBCS. The four components of evaluation were: (1) degree of concordance, (2) distribution across concern levels, (3) discriminating ability of the scheme, and (4) ease of use. At least one of the 20 reference foods was assigned to each of the possible concern levels, demonstrating the ability of the scheme to identify GM foods of different concern with respect to potential health risk. There was reasonably good concordance between the two raters for the three separate parts of the RBCS. The raters agreed that the criteria in the scheme were sufficiently clear in discriminating reference foods into different concern levels, and that with some experience, the scheme was reasonably easy to use. Specific issues and suggestions for improvements identified in the concordance study are discussed.
LANGUAGE: eng
DATE OF PUBLICATION: 2008 Dec
DATE OF ELECTRONIC PUBLICATION: 20080815
DATE COMPLETED: 20090227
DATE REVISED: 20081125
MESH DATE: 2009/02/28 09:00
EDAT: 2008/09/04 09:00
STATUS: MEDLINE
PUBLICATION STATUS: ppublish
LOCATION IDENTIFIER: 10.1016/j.yrtph.2008.08.003 [doi]
OWNER: NLM
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Chief Risk Scientist
Dr. Daniel Krewski is Chief Risk Scientist and co-founder of Risk Sciences International (RSI), a firm established in 2006 to bring evidence-based, multidisciplinary expertise to the challenge of understanding, managing, and communicating risk. As RSI’s inaugural CEO and long-time scientific...