Risk Sciences International (RSI) is excited to announce the release of Epicure 2.0 for Windows, the first official release of the window-based version of the premiere software for risk regression and person-year tabulation. The following sections provide an overview of the history and functionality of Epicure and highlight some of the new features.

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RSI supports signal detection in safety surveillance, environmental monitoring, and early warning systems. Its teams configure thresholds, monitor trends, and use algorithms or human-in-the-loop processes to flag concerns. RSI emphasizes the integration of signal detection with context interpretation, ensuring appropriate responses and sustained vigilance.

RSI conducts emergency gap analyses that link risk scenarios with operational realities. Its approach combines tabletop exercises, stakeholder consultation, and systems modeling to assess functional readiness. RSI frames gaps in terms of actionable priorities and supports clients in developing roadmaps for remediation. This method integrates seamlessly with RSI’s broader risk understanding and emergency planning capabilities.

To support decision-making around modifications to opioid agonist treatment delivery, a detailed risk assessment was requested to evaluate the integration of secure dispensing devices for direct patient access to hydromorphone. Building on a previously conducted preliminary assessment, the work required a structured framework that would articulate hazards, assess likelihoods and risks, and identify mitigation strategies associated with introducing these devices into service delivery models.

A large number of domestic and foreign animal diseases with zoonotic health impacts to humans must be managed carefully to prevent disease transmission and spread. Risk management decisions often involve the comparison of different types of risk and the cost-effectiveness of different control measures for reducing risk. This requires that different types of risk be assessed in a consistent manner to allow cross-comparisons. The use of disability adjusted life years (DALYs) as a measure of the burden of human disease from domestic and foreign animal pathogens was completed for several zoonoses in Canada.

Margaret Wilson is a Senior Risk Analyst at Risk Sciences International (RSI), where she has been a foundational member since the company’s inception in 2006. Drawing on a rare combination of scientific breadth and analytical precision, Margaret has supported and led a wide range of multidisciplinary projects spanning microbial and chemical food safety, prion diseases, climate-related risk prioritization, and global regulatory systems.

RSI supports clients in developing or revising thresholds used in regulation, screening, or monitoring. It combines data modeling, stakeholder input, and expert judgment to define points that are both scientifically grounded and operationally feasible. RSI documents the rationale and implications of threshold choices to support implementation.

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RSI supports clients in building comprehensive and structured risk inventories, tailored to sector-specific frameworks. It uses standardized templates, taxonomies, and stakeholder input to ensure coverage and relevance. RSI’s inventories are designed for integration into ongoing risk governance and decision-support systems.