Preliminary evidence-based risk assessment framework

Evidence-based Risk Assessment Framework

December 12, 2022
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Working with international thought leaders in risk science, Risk Sciences International investigators contributed to the development of the evidenced-based risk assessment framework shown in the figure below.  The framework evolved from a workshop held at the University of Ottawa in December 2018, jointly organized by the McLaughlin Centre for Population Health Risk…

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Problem-formulation-food-safety-assessments

Food safety assessments

November 17, 2022
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Problem Formulation in Food Safety Assessments conducted by the European Food Safety Authority RSI investigators recently provided advise to the European Food Safety Authority (EFSA) on the problem formulation step in the EFSA scientific assessment approach shown in the figure below.  The recommended problem formulation framework is designed to translate the mandate into well-formulated assessment questions…

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VOI paper in Risk Analysis

Value of information analysis framework

October 28, 2022
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In its 2007 report on Toxicity Testing in the 21st Century: A Vision and a Strategy, the US National Research Council  (NRC) highlighted need for more rapid toxicity testing strategies in order to expand the coverage of the large number of chemicals for which toxicological data is lacking. This need was further…

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Principles of risk decision-making

August 19, 2022
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RSI investigators propose fundamental principles of risk decision-making, and explore their application in a range of real-world risk decision-making contexts. These ten principles will provide valuable guidance on addressing current and future risk issues facing civil societies worldwide.

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Risk Sciences International 1

Paul Price

July 14, 2022
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Dr. Paul Price is an exposure and risk assessor who has recently retired from the Office of Research and Development of the U.S. Environmental Protection Agency. He is an adjunct professor at the University of Iowa and a frequent guest lecturer. Dr. Price is active in the area of mixtures risk assessment. He is president of the Mixtures Specialty Section of the Society of Toxicology and has recently given a continuing education course on risks from combined exposures. Dr. Price serves on the European Food Safety Authority’s committee on risks from combined exposures. He was an invited speaker for the 2022 “ONE conference” in Brussels. Dr. Price is currently working on multiple publications on mixture risk assessment and the Mixture Adjustment Factor.

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Peter Aggett

June 27, 2022
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Peter Aggett is a Paediatrician with an interest in Gastroenterology, Metabolism and Chemical Pathology. His focus has been on essential trace elements in health and disease. He is Emeritus Head of Lancashire School of Health and Postgraduate Medicine and Professor of Child Health and Nutrition at the University of Central…

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Paul Stanish

May 26, 2022
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Paul Stanish joined Risk Sciences International in 2021 as a Risk Analyst. Paul’s current focus is on using emerging tools to modernize client’s understanding risk and streamline and rationalize their data culture.

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Risk of Myocarditis and Pericarditis

May 11, 2022
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Using data from the US Centers for Disease Control (CDC) Vaccine Adverse Event Reporting System, RSI investigators collaborated on a study showing increased risks of myopericarditis – an inflammatory condition of the heart muscle – following mRNA COVID19 vaccination, with the highest risks seen in young males following a second…

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Quinolones

Quinolones and risk of retinal detachment

April 26, 2022
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Following previous work on the potential risk of acute liver failure associated with quinolone antibiotics, RSI investigators, Mohamed Taher, Franco Momoli, Donald Mattison and Daniel Krewski evaluated the potential risk of retinal detachment (RD) associated with these medications. Although no cases of RD were linked to quinolones in clinical trials, some…

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IAI Climate Change report

IAI climate change report

April 12, 2022
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The International Aluminium Institute (IAI) recently commissioned Climate Risk Institute (CRI) and Risk Sciences International (RSI) to produce a series of informational tools evaluating and explaining the future effects of climate change on the aluminium sector’s sustainability. A principle focus of the project was to highlight one of the most…

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