Risk Sciences International (RSI) investigators Greg Paoli, Shintaro Hagiwara and Daniel Krewski collaborated with investigators from the US Center for Computational Toxicology and Exposure (CCTE) on the development of an analytical framework to evaluate alternative chemical toxicity testing strategies, meeting a need identified by the US National Research Council in its 2009 report on Science and…

Risk Sciences International (RSI) is pleased to announce in collaboration with the Ontario Centre for Climate Impacts and Adaptation Resources (OCCIAR), the public release of “Best Practices for Consideration of the Effects of Climate Change in Project-Level Assessments”.   The Best Practices document is available at RSI, CONTACT US HERE for a copy. The authoring team…

Adverse effects of drugs among the elderly should be given special attention when considering a pharmacological intervention. Two recent papers using large electronic health records have explored the impact of drugs with anticholinergic properties. The first, “Associations between Anticholinergic Burden and Adverse Health Outcomes in Parkinson Disease” view here used a HealthFacts database (Cerner Corporation, Kansas…

Compounded medications prepared by pharmacists or physicians have been used extensively throughout history as a mainstay of therapeutics.  Over the past half-century – with the increasing focus on evidence based treatment the use of compounded medications substantially decreased.  However, in some therapeutic areas, such as menopause, use of compounded medications continues.  The continuation of use…

Using data from the US Centers for Disease Control (CDC) Vaccine Adverse Event Reporting System, RSI investigators collaborated on a study showing increased risks of myopericarditis – an inflammatory condition of the heart muscle – following mRNA COVID19 vaccination, with the highest risks seen in young males following a second vaccine dose.  Similar findings have…

CPS has recently announced 13 new research awards totaling a little over $2.6 million. The awards are for research projects directed at answering critical questions in specific areas of food safety practices. Among this year’s topics: storage, sanitation, agricultural water, co-management and risk-based field sampling. Projects will begin in January 2019. RSI’s Emma Hartnett is…

The Center for Alternatives to Animal Testing and the Animal-Free Safety Assessment recently held their annual meeting on advancing toxicity testing in the 21st century (TT21C). This informal event provided brief updates on cutting edge approaches in toxicology that have accrued since the publication of the 2007 U.S. National Research Council report on Toxicity Testing…

Calvin C. Willhite, an Associate Expert with Risk Sciences International working on a range of toxicological risk issues, was just announced as the recipient of the prestigious 2021 Arnold Lehman Award presented annually by the Society of Toxicology for outstanding contributions to evidence-based toxicology to improve public health. Dr. Willhite specializes in human health risk assessments for man-made…

Following up on the recommendations put forth by the Expert Management Panel on River Flood Mitigation, the Environmental and Safety Management (ESM) and Water Resources (WS) business units of the City of Calgary are currently assessing how to best develop a suite of watershed-scale climate models to capture various weather event scenarios that may affect the…

RSI is pleased to be the recipient of funding through the DND IDEaS COVID-19 Challenge. Under the supervision of Emma Hartnett, RSI will be developing a risk-based tool to support public health emergency response planning for COVID-19, and other infectious disease and mass casualty emergencies in the future. The safety and well-being of Canadians are…