To support the Chemicals Management Plan under the Canadian Environmental Protection Act (CEPA), Health Canada sought expert peer consultation for a draft screening assessment report (DSAR) evaluating 47 inorganic substances identified as priorities. The client required independent scientific and technical expertise to assess whether the report’s conclusions—particularly regarding health effects, exposure pathways, and risk characterizations—were sound, complete, and defensible.

The project centered on supporting the development of a methodology that could eventually be implemented as an Artificial Intelligence (AI) or Machine Learning (ML) process. The objective was to help formalize and potentially automate how professional judgment is applied when determining the risk significance of non-compliant findings within the Canadian nuclear regulatory framework. Specifically, the…

To support the quality and defensibility of regulatory decision-making under the Canadian Environmental Protection Act, 1999 (CEPA), Health Canada engaged Risk Sciences International to coordinate an independent external peer review of the Draft Screening Assessment Report (DSAR) for Selected C3-C5 Alcohols, focusing specifically on tert-butanol (CAS RN 75-65-0). This group of substances had been prioritized for risk assessment based on potential human health concerns.

To support the evaluation of a new veterinary pharmaceutical product intended for use in bovines, a scientific review was requested of submitted toxicological data related to the active compound LY488756. This compound, proposed under the product name Experior, had been advanced for registration based on its claimed selective action on β3-adrenergic receptors and a lack of mutagenic, carcinogenic, or teratogenic effects. Given its potential entry into the human food supply via meat residues, an independent expert analysis of the submission was deemed necessary to determine its safety.

A federal agency required scientific support to enhance the effectiveness of its environmental enforcement activities. This involved identifying and analyzing the risk factors—both environmental and human health-related—that contribute to the likelihood and impact of regulatory offences. The objective was to develop a structured approach to prioritize enforcement actions under key legislative frameworks including the Canadian Environmental Protection Act, the Fisheries Act, the Species at Risk Act, and others.

To support more effective health policy and pandemic preparedness, this project examined how environmental health factors intersect with chronic disease and influence pandemic resilience. The client sought evidence to clarify how exposures to contaminants in air, water, and soil contribute to the environmental burden of disease in Canada and exacerbate vulnerability to infectious disease outcomes, including COVID-19.

The College of Physicians & Surgeons of Alberta (CPSA) commissioned a systematic review and meta-analysis to support evidence-informed decision-making around age-related cognitive decline among practicing physicians. The initiative was led by CPSA’s Physician Health Monitoring Program (PHMP), which sought to ensure continued competence and public safety in the context of an aging medical workforce.

The project began with a series of consultations with UN-Habitat at UNON in Nairobi. In addition to Cemil Alyanak and Nicholas you, the project grew to include many key stakeholders both within UN-Habitat and from other organizations. Among the key organizations included in the early stages were United Cities and Local Governments, Cities Alliance, the World Bank, Habitat for Humanity, Cisco, and UN agencies interested in urban health, notably the World Health Organization.

An international airport authority sought a comprehensive assessment of passenger and vehicle traffic flow after receiving complaints of confusion and safety concerns. Reports indicated that passengers were struggling to interpret signage, often stopping too long to process graphics, which caused line-ups and delays. Lighting problems compounded the issue, with signs placed in poorly illuminated areas.…