Facing renewed challenges in securing a reliable domestic plasma supply, Canadian Blood Services sought support to apply a Risk-Based Decision-Making (RBDM) framework. The objective was to assess the value and implications of expanding domestic plasma collection and processing capacity in response to the emergence of commercial plasma operations that export plasma to international markets.

To support the evaluation of a new veterinary pharmaceutical product intended for use in bovines, a scientific review was requested of submitted toxicological data related to the active compound LY488756. This compound, proposed under the product name Experior, had been advanced for registration based on its claimed selective action on β3-adrenergic receptors and a lack of mutagenic, carcinogenic, or teratogenic effects. Given its potential entry into the human food supply via meat residues, an independent expert analysis of the submission was deemed necessary to determine its safety.

An independent regulatory organization responsible for oversight of Alberta’s safety codes system sought to strengthen its capacity for risk-based decision-making. The organization aimed to ensure that regulatory actions—particularly in the area of petroleum storage tanks—were guided by clear, evidence-based prioritization methods that protect public safety while making effective use of resources. The project began with…

To support decision-making around modifications to opioid agonist treatment delivery, a detailed risk assessment was requested to evaluate the integration of secure dispensing devices for direct patient access to hydromorphone. Building on a previously conducted preliminary assessment, the work required a structured framework that would articulate hazards, assess likelihoods and risks, and identify mitigation strategies associated with introducing these devices into service delivery models.

To enhance the methodological rigour of its scientific assessments, EFSA sought to develop a standardised framework for problem formulation (PF) within its non-application scientific assessment protocols. The goal was to support the planning phase of these assessments by establishing a structured, reproducible approach for translating mandates into scientifically answerable questions. This included creating a framework…

The College of Physicians & Surgeons of Alberta (CPSA) commissioned a systematic review and meta-analysis to support evidence-informed decision-making around age-related cognitive decline among practicing physicians. The initiative was led by CPSA’s Physician Health Monitoring Program (PHMP), which sought to ensure continued competence and public safety in the context of an aging medical workforce.

Environment and Climate Change Canada, with Health Canada, wanted to understand perceptions of the health risks from smoke from wildfires and from residential burning (winter heating using wood stoves, and fireplaces), and public health communication approaches and messages used in these contexts. This information would support revisions of the health messages used in the Air Quality Health Index (AQHI). The AQHI expresses the health risk associated with three common urban air pollutants, and is calculated at monitoring stations in communities across Canada to inform the public of the risk level of current local air quality conditions.

To support its Standards to Support Resilient Infrastructure Program, the Standards Council of Canada (SCC) launched a national consultation campaign to identify and prioritize climate-related standardization needs. SCC required a flexible risk prioritization framework to evaluate the relative urgency and impact of various standardization topics related to climate change adaptation and mitigation, especially in the infrastructure sector.

The client sought support to finalize a Commission Member Document (CMD) for the re‑licensing of a nuclear facility. Recognizing the complexity and sensitivity of reactor re‑licensing, they requested assistance in crafting communication materials that were both technically comprehensive and accessible to regulatory bodies and broader audiences. The work included drafting a clear and well‑structured CMD,…