Publication related to RSI or an RSI staff member

Application of a framework for the selection of an appropriate occupational exposure limit for manganese.

Authors

  • Deveau, Michelle, Deveau M, McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, K1N 6N5, Canada. Electronic address: michelle.deveau@uottawa.ca.

  • Maier, Andrew, Maier A, Department of Environmental Health, College of Medicine, University of Cincinnati, Cincinnati, OH, 45267-0056, United States.

  • Krewski, Daniel, Krewski D, McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, K1N 6N5, Canada.

YEAR OF PUBLICATION: 2017
SOURCE: Neurotoxicology. 2017 Jan;58:249-256. doi: 10.1016/j.neuro.2016.09.014. Epub 2016 Sep 20.
JOURNAL TITLE ABBREVIATION: Neurotoxicology
JOURNAL TITLE: Neurotoxicology
ISSN: 1872-9711 (Electronic) 0161-813X (Linking)
VOLUME: 58
PAGES: 249-256
PLACE OF PUBLICATION: Netherlands
ABSTRACT:

Occupational exposure limits (OELs) serve as benchmarks for the interpretation of workplace exposures within a health risk context. Different organizations derive OELs for many chemicals, including manganese. OELs recommended by different organizations can vary quantitatively, which can present a challenge to occupational hygienists or other risk managers that need to select a value for decision-making purposes. In this article, we illustrate the application of a previously-developed OEL selection framework to demonstrate the decisions that would be required to select the most appropriate OEL for various manganese exposure scenarios. The framework helped to identify the need to focus an evaluation on three quantitatively similar values-the ACGIH TLV, SCOEL IOELV, and DFG MAK. These values were compared with regulatory standards and considered for their relevance and reliability. The OEL selection framework was a useful tool in guiding the selection process for manganese OELs.

COPYRIGHT INFORMATION: Copyright (c) 2016 Elsevier B.V. All rights reserved.
LANGUAGE: eng
DATE OF PUBLICATION: 2017 Jan
DATE OF ELECTRONIC PUBLICATION: 20160920
DATE COMPLETED: 20171124
DATE REVISED: 20220321
MESH DATE: 2017/11/29 06:00
EDAT: 2016/09/25 06:00
STATUS: MEDLINE
PUBLICATION STATUS: ppublish
LOCATION IDENTIFIER: S0161-813X(16)30194-2 [pii] 10.1016/j.neuro.2016.09.014 [doi]
OWNER: NLM

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