RSI Expert-Michael G Tyshenko

Michael G. Tyshenko

Senior Health Risk Analyst

Joined RSI in 2018

  • Accomplished research scientist in molecular and cellular biology

  • McLaughlin Chair recipient, University of Ottawa (5-year endowed position)

  • Interdisciplinary training in Public Health and Administration (Queen's University, MPA)

  • International health policy teaching experience in China and Latin America

  • Over 100 peer review publications, 12 book chapters and 2 books

Dr. Michael G. Tyshenko is a Senior Health Risk Analyst at Risk Sciences International (RSI), where he has contributed since 2018 to some of the organization’s most complex and cross-cutting public health risk projects. As RSI’s lead on chemical peer reviews, he brings extensive experience in regulatory science, biological risk, and science-policy integration to high-stakes evaluations that require both deep expertise and clear communication.

Dr. Tyshenko’s research and collaborations span pandemic preparedness, emerging infectious diseases, and global risk policy, with applied work on SARS, MERS, and COVID-19. His current projects include policy analysis for the World Health Organization’s Global Technical Strategy for Malaria 2016–2030, identifying barriers to malaria reduction targets in Sub-Saharan African countries; ongoing collaboration with Nepal’s Ministry of Health on mobile and e-health approaches for remote populations; and ecological climate modeling with partners in Egypt and Saudi Arabia to project how climate change may alter pest distributions affecting biodiversity and crop productivity—providing insights for adaptive management and agricultural resilience.

Drawing on more than two decades of experience at the intersection of risk science, epidemiology, and public health policy, Dr. Tyshenko is recognized for advancing interdisciplinary approaches to health risk evaluation and for bridging scientific evidence with actionable policy.

Pre-RSI

Dr. Tyshenko’s career has consistently bridged the life sciences, public health, and public administration. He holds a Ph.D. and M.Sc. in Biology from Queen’s University, completed postdoctoral training in Public Health at the University of Ottawa, and earned a second master’s degree—a Master of Public Administration—also from Queen’s. This rare combination of scientific and governance-focused training underpins his distinctive contributions to health risk analysis and policy engagement.

From 2009 to 2013, Dr. Tyshenko held the McLaughlin Chair in Biological Risk Assessment at the University of Ottawa, where he led both academic research and applied science-policy translation. During this time, he developed and delivered Johns Hopkins–style short courses in public health across China through a five-year collaborative university–government initiative, and completed a parallel two-year project in Costa Rica, partnering with local and national authorities to identify public health policy gaps and capacity needs.

His leadership extended to the digital realm as Scientific Director of Risk.com, a knowledge portal providing curated summaries of global health hazards. Over the course of his career, Dr. Tyshenko has authored more than 100 peer-reviewed articles, 12 book chapters, and two books—cementing his reputation as a versatile thinker capable of bridging scientific disciplines and policy environments.

Celebrating Nepal’s Constitution Day with Mr. Bhrigu Dhungana, Nepal’s ambassador to Canada. Our work on sustainability in Nepal resulted in the IUCN sponsored book, Sustainable Livelihood Systems in Nepal where I acted and the English copy editor and contributor. A second project involved needs assessments for expanding mountain tourism in Nepal. (Sept. 19, 2022).

Case studies associated with Michael G. Tyshenko

EFSA Framework for Problem Formulation

PROJECT DESCRIPTION

To enhance the methodological rigour of its scientific assessments, EFSA sought to develop a standardised framework for problem formulation (PF) within its non-application scientific assessment protocols. The goal was to support the planning phase of these assessments by establishing a...
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Expansion of the Stochastic Health Canada Quantitative Microbial Risk Assessment Tool

PROJECT DESCRIPTION

Health Canada sought to enhance its Quantitative Microbial Risk Assessment (QMRA) tool, originally developed over 15 years ago for stakeholders responsible for drinking water systems. With advancements in probabilistic modeling and microbial risk assessment, the client required updates to reflect...
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Measuring impact of zoonotic animal diseases in Canada

PROJECT DESCRIPTION

The Canadian Food Inspection Agency sought RSI’s support in exploring how human health impacts from zoonotic diseases could be compared consistently with other public health risks. Traditionally, animal disease control decisions relied on veterinary and economic measures, but there was...
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Finalization of Risk Assessment on Secure Opioid Dispensing Devices

PROJECT DESCRIPTION

To support decision-making around modifications to opioid agonist treatment delivery, a detailed risk assessment was requested to evaluate the integration of secure dispensing devices for direct patient access to hydromorphone. Building on a previously conducted preliminary assessment, the work required...
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External Peer Review of the Draft Screening Assessment Report on Selected C3-C5 Alcohols

PROJECT DESCRIPTION

To support the quality and defensibility of regulatory decision-making under the Canadian Environmental Protection Act, 1999 (CEPA), Health Canada engaged Risk Sciences International to coordinate an independent external peer review of the Draft Screening Assessment Report (DSAR) for Selected C3-C5...
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External Peer Consultation of the Inorganic – Late Biomonitoring Approach Draft Screening Assessment Report

PROJECT DESCRIPTION

To support the Chemicals Management Plan under the Canadian Environmental Protection Act (CEPA), Health Canada sought expert peer consultation for a draft screening assessment report (DSAR) evaluating 47 inorganic substances identified as priorities. The client required independent scientific and technical...
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Publications associated with Michael G. Tyshenko

Multi-jurisdictional expert opinion for improving children’s environmental health protection.


ABSTRACT

Expert opinion from Canada, the United States and European Union countries was solicited to examine the regulatory and non-regulatory approaches used to protect children's environmental health. Thirty-five experts were interviewed by telephone from June 2004 to March 2005 using an...
Publication details about Multi-jurisdictional expert opinion for improving children’s environmental health protection.

The impact of social amplification and attenuation of risk and the public reaction to mad cow disease in Canada.


ABSTRACT

Following the detection of bovine spongiform encephalopathy (BSE) in Canada, and subsequently in the United States, confidence in the safety of beef products remained high. Consumers actually increased their consumption of beef slightly after the news of an increased risk...
Publication details about The impact of social amplification and attenuation of risk and the public reaction to mad cow disease in Canada.

Prionet Canada: a network of centres of excellence for research into prions and prion diseases.


ABSTRACT

PrioNet Canada's strength in basic, applied, and social research is helping to solve the food, health safety, and socioeconomic problems associated with prion diseases. Prion diseases are transmissible, fatal neurodegenerative diseases of humans and animals. Examples of prion diseases include...
Publication details about Prionet Canada: a network of centres of excellence for research into prions and prion diseases.

Risk communication of endocrine-disrupting chemicals: improving knowledge translation and transfer.


ABSTRACT

Public perception of the negative effects of endocrine-disrupting chemicals appears to be higher compared to other chemical pollutants, due to (1) chronic, low-probability effects, and (2) uncertainties about which biological effects may be relevant for human health. Individuals, both expert...
Publication details about Risk communication of endocrine-disrupting chemicals: improving knowledge translation and transfer.

Locust retinoid X receptors: 9-Cis-retinoic acid in embryos from a primitive insect.


ABSTRACT

The retinoid X receptor (RXR) is activated by its often elusive cognate ligand, 9-cis-retinoic acid (9-cis-RA). In flies and moths, molting is mediated by a heterodimer ecdysone receptor consisting of the ecdysone monomer (EcR) and an RXR homolog, ultraspiracle (USP);...
Publication details about Locust retinoid X receptors: 9-Cis-retinoic acid in embryos from a primitive insect.

Men having sex with men donor deferral risk assessment: an analysis using risk management principles.


ABSTRACT

This article discusses issues associated with the lifetime deferral from donating blood of men having sex with men (MSM), in the context of well-established risk management principles, including ethical considerations associated with the risk-based approach to social policy matters. Specifically,...
Publication details about Men having sex with men donor deferral risk assessment: an analysis using risk management principles.

Bovine spongiform encephalopathy and the safety of milk from Canadian dairy cattle.


ABSTRACT

The detection of bovine spongiform encephalopathy (BSE) in beef cattle closed Canadian beef export markets to 30 countries, including the USA, with devastating financial losses. The detection and confirmation of the fifth and seventh BSE-infected animals but first infected dairy...
Publication details about Bovine spongiform encephalopathy and the safety of milk from Canadian dairy cattle.

Transcription of antifreeze protein genes in Choristoneura fumiferana.


ABSTRACT

Antifreeze proteins (AFPs) are encoded by approximately 17 genes in the spruce budworm, Choristoneura fumiferana. Northern analysis using 6 different cDNA probes showed isoform-specific patterns that varied during development. Transcripts for the majority of isoforms were most abundant in the...
Publication details about Transcription of antifreeze protein genes in Choristoneura fumiferana.

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Expert editorials associated with Michael G. Tyshenko

Machine Learning and Risk Assessments – Are Humans Obsolete?

Human health risk assessment is a well-established methodology that identifies and quantifies the potential risk of adverse health effects in humans who may be exposed to chemical contaminants in environmental media, such as air, water, soil, and food (Fryer et al., 2006).  Human health risk assessments can extend to other areas...
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Outside RSI

Beyond his professional life, Dr. Tyshenko is a dedicated and accomplished triathlete, with over 100 Olympic-distance triathlons, multiple Half-Ironman races, and three Ironman completions to his name. He has represented Canada as an age-group athlete at the World Triathlon Championships in Deerhurst, later transitioning to longer endurance formats that echo the persistence and discipline he brings to his scientific work.

Dr. Tyshenko’s approach to public health is fundamentally holistic—integrating molecular biology, risk communication, ethics, and evidence-based policymaking. His athletic discipline, global perspective, and interdisciplinary fluency make him a valued contributor to RSI’s mission to understand, manage, and communicate health risks in a rapidly changing world.

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