EPICURE

The premiere software for risk regression and person-year tabulation

Epicure-1

Introduction

What is EPICURE?

Risk Sciences International (RSI) is excited to announce the release of Epicure 2.0 for Windows, the first official release of the window-based version of the premiere software for risk regression and person-year tabulation. The following sections provide an overview of the history and functionality of Epicure and highlight some of the new features.

See below for information on pricing.

For additional information please visit: http://epicurehelp.risksciences.com. To request a demo version or to purchase Epicure, contact us.

The Tool

EPICURE: what to expect

RSI, acquired Epicure from Hirosoft International Corporation, and is marketing Epicure while actively working with Dale Preston and his colleagues to improve and enhance Epicure’s capabilities.

Brief History and Description of Epicure

Epicure was originally developed for regression modeling of radiation effects on cancer rates in atomic bomb survivors. The development was motivated by the recognition that models focused on the excess relative risk (i.e. the RR-1) were more suitable for describing dose response and effect modification than the loglinear Cox-regression proportional hazards model and by the need for explicitly modeling excess rates (rate differences) as a function of dose and other, often time-dependent, factors.

For almost 30 years, Epicure has provided a powerful set of tools for risk regression using a rich class of models that extends the commonly used log-linear relative risk (Cox regression) and relative odds (logistic regression) models to include excess relative risk / odds models and excess rate models. Epicure also includes a module for the straightforward specification and creation of highly stratified person-year (or more generally event-time) tables including, as needed, stratification on multiple time scales and time-dependent factors (such as lagged cumulative doses).

Epicure is an interactive, command-driven program with a simple and intuitive, b ut powerful scripting language. This new release features a graphical user interface that makes the program even easier to use.

While Epicure is the de-facto standard for modeling radiation health effects, the models and methods in Epicure have been used for a wide variety of medical, public health, epidemiological, economic, environmental, and reliability data. The methods are particularly useful for dose-response modeling and investigating joint effects of and interactions between multiple risk factors.

Epicure’s DATAB module is the most powerful and flexible tool available for creating high dimensional person year (event-time) tables for use in Poisson-regression-based analyses of survival data including analysis of standardized mortality/incidence ratios.

RSI's EPICURE offer in greater detail

Epicure Risk Model Examples

The following examples describe some of the models that can be used for modeling risks and rates in Epicure. Additional details are available in the online manuals (http://epicurehelp.risksciences.com).

Classical relative risk / relative odds models:

baseline*RR

baseline – non-parametric, stratified, fully parametric

RR – typically log-linear ()

  • Includes the semi-parametric standard proportional hazards model, Cox regression ()
  • Fully stratified or parametric baseline rate/risk models can also be used
  • General time-dependent covariates
Excess relative risk / excess odds ratio:

ERR – excess relative risk

  • Models include simple dose response models:   e.g., or
    • Easily fit categorical, threshold, and spline dose-response models
  • Multiplicative effect modification: e.g. where x could include fixed (e.g., exposure age, sex) or time-dependent (e.g. age, time since exposure) factors
Joint effects for excess relative risk / excess odds ratio:

additive excess relative risk

   multiplicative excess relative risk model

  • Examples include joint effects of chemical exposure (ERR1) and smoking (ERR2)
  • Up to four excess relative risk terms
  • Can model joint effects as geometric mixture of additive and multiplicative models
Risk difference / Excess rate / excess odds models†:

  • Up to four excess absolute rate terms
  • Excess absolute rate terms have same form as ERR terms
  • †    risk difference modeling requires parametric baseline model

Epicure Risk Regression Modules

GMBO / PECAN – Binomial data including conditional and unconditional logistic regression

  • Matched (conditional) and unmatched logistic regression for odds ratios in case-control studies
  • Stratified logistic regression
  • Regression analyses of probabilities and log(probabilities)
  • User-defined variance functions for over-dispersed data

PEANUTS –Partial-likelihood methods for censored survival data (including Cox regression)

  • Easily define and use general user-defined time-dependent covariates
  • Case-cohort data
  • Allows late entry data
  • Kaplan-Meier and Nelson-Aalen non-parametric estimates

AMFIT – Grouped survival / (Poisson (piecewise constant hazard) data

  • Relative risk and rate difference models
  • Efficient handling of time-dependent covariates
  • Either fully or semi-parametric hazard functions in relative risk models
  • Standardized mortality/incidence ratio analyses

Person-year (rate) table creation (DATAB Module)

  • Easily create multi-dimensional event-time (person-year / rate) tables
  • Multiple category variables
  • Simple specification of categories
  • Multiple time scales (e.g. attained age, time since exposure/diagnosis, calendar time)
  • User-defined time category boundaries
  • Calendar time or user defined time scales
  • Time dependent categories (e.g. lagged cumulative dose, years smoked, time-since-smoking cessation)
  • Multiple summary variables (case counts, cell-specific means etc.)
  • Easy to add external rates or job-exposure-matrix values

Epicure Features

Powerful tools for dealing with time-dependent exposures and risks
Easy to use standard models or to extend to more general risk models
  • Excess relative risk models
  • Excess rate models
  • Additive and multiplicative models for joint effects
  • Simple model specification
Likelihood-based inference
  • Asymptotic-normality-based (Wald) test and confidence bounds
  • Score tests
  • Likelihood ratio tests
  • Profile likelihoods and likelihood-based bounds
  • Efficient procedures for fitting stratified regression models
  • Create multi-dimensional person-year tables with user-defined time-dependent categories
  • Simple, but useful tools for summarizing and plotting data
Interactive
  • Create new variables as needed
  • Designed for interactive modeling
  • Easily select subsets
  • Simple creation of categorical variables from continuous variables
  • Command driven scripting with a graphical user interface

What’s New

  • Windows-based graphical user interface
  • Multiplicative ERR models
  • Linear parameter constraints in regression models
  • Improved case-cohort modeling (PEANUTS)
  • Simplified input from delimited (comma, tab, space) text files with variable name headers
  • Array functions to simplify computation of time-dependent events such as cumulative doses
  • External dataset lookup available as a function (with up to six levels of indexing) in both DATAB and the regression modules.
  • Enhanced data export routines
  • Improved output of model form and parameter estimate data (easily readable in commonly used statistical packages)
  • Save ungrouped person year data (one record for each cell in which a “person” is at risk) to text file to facilitate minimally grouped Poisson regression analyses of survival data. Useful for data with many risk factors or for post-hoc analyses of covariate (e.g. dose) uncertainties.
  • Improved automatic session logging
  • Context sensitive help

Ordering Epicure

A single user license is 1200 USD but licensed users of the previous edition of Epicure can upgrade for 750 USD.

Optional annual maintenance is 240 USD. Our discount program is outlined below:

  • Full price for the first license
  • 10% off the second
  • 15% for the third
  • 20% for the fourth
  • 25% off any additional licenses

Contact epicure@risksciences.com if you need more information about Epicure models and features.

If you wish to purchase Epicure 2.0, please provide us with your billing details and indicate how many licenses you would like to purchase.

Selected examples of analyses using EPICURE:

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Clients and Stakeholders

400+

Gov & IGO

Federal, regional and local government authorities and international/multilateral organizations including the United Nations and UN Agencies:
 

  1. Aboriginal Affairs and Northern Development Canada (AANDC)
  2. Agency for Food, Environmental and Occupational Health & Safety (ANSES)
  3. Agriculture - Agri-Food Canada (AAFC)
  4. Alberta Health and Wellness Services
  5. Arctic Aquatic Research Division
  6. Australian Food Safety Centre (FSC)
  7. Basel Convention on the Transboundary Movement of Hazardous Waste
  8. BC Centre for Disease Control (BCCDC)
  9. BC Ministry of Environment (BCMoE)
  10. BC Ministry of Transport (BCMoT)
  11. Canadian Food Inspection Agency (CFIA)
  12. Canadian Heritage (PCH)
  13. Center for Food Safety and Applied Nutrition (CFSAN) of FDA
  14. Central Research Institute of Japan
  15. China Institute for Radiation Protection
  16. Chinese Center for Disease Control & Prevention
  17. City of Barrie
  18. City of Calgary
  19. City of Kingston
  20. City of Mississauga
  21. City of Ottawa
  22. City of Toronto
  23. Community of Federal Regulators (CFR)
  24. Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES)
  25. Credit Valley Conservation Authority (CVCA)
  26. Crown Indigenous and Northern Affairs (CIRNA)
  27. Defence Research and Development Canada (DRDC)
  28. Dene First Nation
  29. Department of Finance Canada (FIN)
  30. Department of Health, UK
  31. Department of Justice Canada (JUS)
  32. Department of National Defence (DND)
  33. Environment and Climate Change Canada (ECCC)
  34. Environmental Commission of Ontario (ECO)
  35. European Broadcasting Union (EBU)
  36. European Free Trade Agreement (EFTA)
  37. European Union (EU)
  38. Fisheries & Oceans Canada (DFO)
  39. Food and Agriculture Organization of the United Nations (FAO)
  40. Food Protection and Defense Institute (FPDI)
  41. GIZ
  42. Global Fund to Fight AIDS, Tuberculosis and Malaria
  43. Global Observatory for eHealth (WHO)
  44. Global Strategy on Diet, Physical Activity and Health (WHO)
  45. Government of New Brunswick (GNB)
  46. Government of Northwest Territories (GNWT)
  47. Greater Vancouver Regional District
  48. Green Cross International (GCI)
  49. Health Canada (HC)
  50. Homeland Security Centers of Excellence (HS-Centers) of U.S. Dept of Homeland Security.
  51. Indigenous and Northern Affairs Canada (INAC)
  52. Industry Canada (IC)
  53. International Agency for Research on Cancer (WHO)
  54. International AIDS Society (IAS)
  55. International Air Transport Association (IATA)
  56. International Atomic Energy Agency (IAEA)
  57. International Labour Organization (ILO)
  58. International Organization for Migration (IOM)
  59. International Organization for Standardization (ISO)
  60. International Social Security Association (ISSA)
  61. International Telecommunication Union (ITU)
  62. Japan Atomic Energy Agency
  63. Joint United Nations Programme on HIV/AIDS (UNAIDS)
  64. Lake Simcoe Region Conservation Authority
  65. Measurement Canada (MC)
  66. MetroLinx
  67. National Centre for Food Protection & Defense (NCFPD) Homeland Security Center of Excellence)
  68. National Research Council Canada (NRC)
  69. Natural Resources Canada (NRCan)
  70. New Brunswick Government (GNB), Dept. of Environment and Local Government
  71. Northern Ontario Public Services
  72. Nuclear Regulation Authority (NRA)
  73. Office of the Privacy Commissioner of Canada (OPCC)
  74. Ontario Association for Impact Assessment (OAIA)
  75. Ontario Centre for Climate Impacts and Adaptation Resources (OCCIAR)
  76. Ontario Ministry of Infrastructure
  77. Ontario Ministry of the Environment & Climate Change (OMECC)
  78. Public Health Agency of Canada (PHAC)
  79. Public Health England (PHE)
  80. Public Safety Canada (PSC)
  81. Public Services and Procurement Canada (PSPC)
  82. Public Works and Government Services Canada (PWGSC)
  83. Regional Municipality of Durham
  84. Regional Municipality of Waterloo
  85. RIVM National Institute for Public Health and the Environment
  86. Roll Back Malaria (RBM) Partnership (WHO)
  87. Statistics Canada (StatCan)
  88. Stop TB Partnership
  89. Technical Standards & Safety Authority (TSSA)
  90. Tobacco Free Initiative TFI (WHO)
  91. Toronto and Region Conservation Authority (TRCA)
  92. Toronto Public Health (TPH)
  93. Transport Canada (TC)
  94. Treasury Board Secretariat of Canada (TBS)
  95. UN Watch
  96. UN-Habitat
  97. UNITAID
  98. United Nations (UN)
  99. United Nations Environment Programme (UNEP)
  100. United Nations High Commissioner for Refugees (UNHCR)
  101. United Nations Human Rights (OHCHR)
  102. United Nations Institute for Training and Research (UNITAR)
  103. United Nations International Strategy for Disaster Reduction (UNISDR)
  104. United Nations Volunteers
  105. Universal Postal Union (UPU)
  106. UNplus
  107. US Army Natick Soldier RD&E Center - Combat Feeding Directorate (DFAS)
  108. US Center for Disease Control and Prevention (CDC)
  109. US Dept of Homeland Security (DHS)
  110. US Environmental Protection Agency (EPA)
  111. US Food & Drug Administration (FDA)
  112. USAID Office of Transitional Initiatives
  113. USDA Agricultural Research Service - Eastern Regional Research Center (ARS-ERRC)
  114. USDA Food Safety and Inspection Service (FSIS)
  115. Workplace Safety & Insurance Board (WSIB)
  116. World AIDS Day (WAD)
  117. World Alliance for Patient Safety (WHO)
  118. World Health Day (WHO)
  119. World Health Organization (WHO)
  120. World Health Professions Alliance (WHPA)
  121. World Trade Organization (WTO)
  122. World Urban Campaign (WUC)
  123. World Water Day (WHO)

NGO & PPP

Non-governmental organizations, other civil society organizations, as well as private-public partnerships that RSI has either served or partnered with:
 

  1. 4TRANSIT Joint Venture
  2. Air and Waste Management Association (AWSA)
  3. Aluminium REACH Consortium (ARC)
  4. America Frozen Food Institute (AFFI)
  5. America Water Works Association (AWWA)
  6. Americal Chemistry Council (ACC)
  7. American Blood Centers
  8. American Cancer Society
  9. American Childhood Cancer Organization
  10. BioVision - World Life Sciences Forum
  11. Building and Wood Workers' International (BWI)
  12. Bureau de Normalization du Quebec
  13. Canadian Blood Services (CBS)
  14. Canadian Climate Forum (CCF)
  15. Canadian Conservation Institute (CCI)
  16. Canadian Gas Association (CGA)
  17. Canadian Partnership Against Cancer (CPAC)
  18. Canadian Standards Association (CSA)
  19. Cancer Care Ontario (CCO)
  20. Center for Product Safety (CPS)
  21. Centre for Public Management
  22. Children's Mercy Hospital and Clinics
  23. Children's National Medical Center
  24. Clarity Healthcare
  25. Clean Air Partnership
  26. Climate Risk Institute (CRI)
  27. Clinton Foundation
  28. Conceptis Inc (WebMD)
  29. Council of Canadian Academies
  30. Ecumenical Advocacy Alliance (EAA)
  31. Ecumenical Loan Funds For Human Development (ECLOF)
  32. Europa Donna, The European Breast Cancer Coalition
  33. European Aluminum Association (EAA)
  34. Fonterra Co-Operative Group
  35. Franciscans International (FI)
  36. Global Alliance for Improved Nutrition (GAIN)
  37. Global Forum for Health Research (GFHR)
  38. Global Movement for Children (GMC)
  39. GRACE GmbH - SASforREACH Consortium
  40. ICF International Inc. (ICF)
  41. Institut de Radioprotection et de Sûreté
  42. Institute for Safe Medical Practices (ISMP)
  43. Institute of Food Research (IFR)
  44. International Aluminium Institute (IAI)
  45. International Bridges to Justice (IBJ)
  46. International Catholic Migration Commission (ICMC)
  47. International Centre for Trade and Sustainable Development (ICTSD)
  48. International Copper Association (ICA)
  49. International Council on Mining and Metals Limited (ICMM)
  50. International Federation of Chemical, Energy, Mine and General Workers' Unions (ICEM)
  51. International Federation of Red Cross and Red Crescent Societies (IFRC)
  52. International Federation of University Women (IFUW)
  53. International Hospital Federation
  54. International Institute for Sustainable Development (IISD)
  55. International Life Sciences Institute (ILSI)
  56. International Manganese Institute (IMnI)
  57. International Osteoporosis Foundation (IOF)
  58. International Prevention Research Institute (IPRI)
  59. International Trade Union Confederation (ITUC)
  60. International Union for the Conservation of Nature (IUCN)
  61. ISGlobal Barcelona Institute for Global Health
  62. Joint Expert Meeting on Microbiological Risk Assessment (JEMRA) Tof FAO/WHO
  63. Joint Institute for Food Safety and Applied Nutrition (JIFSAN) UMD-FDA
  64. Korea Institute of Radiological and Medical Sciences
  65. Livestock Innovation Research Corporation (LRIC)
  66. Médecins Sans Frontières (MSF)
  67. Medicines Patent Pool (MPP)
  68. Mining Innovation, Rehabilitation, and Applied Research Corporation (MIRARCO)
  69. Muscular Dystrophy Association (MDA)
  70. National Academy of Sciences (NAS)
  71. National Cancer Institute (NCI)
  72. National Pork Board
  73. Netherlands Cancer Institute
  74. Northern Climate Exchange (NCE)
  75. Nuclear Waste Management Organization (NWMO)
  76. Oak foundation
  77. Ontario Power Generation (OPG)
  78. Ontario Regional Climate Change Consortium (ORCCC)
  79. Organization of African First Ladies Against AIDS (OAFLA)
  80. PregMedic
  81. Public Services International (PSI)
  82. Radiation Effects Research Foundation
  83. Ramsar convention on wetlands
  84. Roswell Park Comprehensive Cancer Center
  85. RTI International
  86. Science and Technology Center in Ukraine
  87. Small Arms Survey
  88. Society for Risk Analysis (SRA)
  89. South Carolina College of Pharmacy
  90. Standards Council of Canada (SCC)
  91. Swiss Federal Nuclear Safety Inspectorate ENSI
  92. The Aluminum Association (AA)
  93. Toronto Community Housing (TCH)
  94. Toxicology Excellence for Risk Assessment
  95. Trade Union Advisory Committee
  96. Union for International Cancer Control (UICC)
  97. Union Network International (UNI)
  98. WaterSMART Solutions Ltd
  99. World AIDS Campaign (WAC)
  100. World Council of Churches (WCC)
  101. World Organization of the Scout Movement (WOSM)
  102. World Wide Fund for Nature (WWF International)
  103. World YWCA Young Women's Christian Association

Business

Companies both large and small:
 

  1. A-Maps Environmental Inc. 
  2. AECOM Canada Limited 
  3. Ajilon Consulting 
  4. Arcelor
  5. Associated Engineering Alberta Ltd. (ASENG)
  6. BGC Engineering Inc.
  7. BMW Gmbh
  8. Bull Hausser and Tupper LLC
  9. Bundesamt für Strahlenschutz
  10. Canadian National (CN)
  11. Coca Cola Company
  12. Copp Clark Ltd.
  13. Crawford and Company Canada Inc
  14. CRDF Global
  15. Dillon Consulting Limited
  16. Dow Chemical Company 
  17. Emdata Co. Ltd. 
  18. Emmons & Olivier Resources Canada Inc. (EOR)
  19. Engineers Canada
  20. ESSA Technologies Ltd. 
  21. Federated Press
  22. FNC Technology Co., Ltd.
  23. Geneva International Airport
  24. Hatch Limited
  25. Helmholtz Zentrum München
  26. Hydro Ottawa
  27. ICF International
  28. Intersol Group Ltd.
  29. Intertek Health Sciences Inc.
  30. IRIS Legal
  31. Japan Nus Company Ltd.
  32. King & Spalding
  33. Lakind Associates LLC
  34. Lansdowne Technologies
  35. Lapointe Engineering Ltd 
  36. Lockheed Martin
  37. Lumina Decision Systems
  38. Manulife Financial Real Estate
  39. MARS Foods (China) Co. Ltd.
  40. Matrix Solutions Inc
  41. McCague Borlack LLP
  42. McCarthy Tetrault LLP
  43. Meat and Livestock Australia
  44. MITACS 
  45. Mondelēz International
  46. Morrison Hershfield
  47. Moto Internationale
  48. Motosport Plus
  49. Nodelcorp Consulting Inc
  50. NORR
  51. Novel Futures Corporation
  52. NTNU Regnskapsseksjonen
  53. Phillips & Paolicelli LLP (P2Law)
  54. Price Waterhouse Coopers (PWC) 
  55. Querencia Partners Ltd.
  56. R.V. Anderson Associates Ltd
  57. Restaino Law Firm
  58. Rio Tinto
  59. RWDI Air Inc 
  60. Science Applications International Corporation (SAIC) 
  61. Social and Scientific Systems, Inc
  62. Stantec Consulting Ltd. 
  63. Summit Toxicology LLP
  64. TetraTech Inc.
  65. Toronto Hydro-Electric System Limited
  66. Torys LLP
  67. TriEdge & Associates
  68. Unilever 
  69. Versar, Inc.
  70. WSPA-Maps Environmental Inc. 
  71. AECOM Canada Limited 
  72. Ajilon Consulting 
  73. Arcelor
  74. Associated Engineering Alberta Ltd. (ASENG)
  75. BGC Engineering Inc.
  76. BMW Gmbh
  77. Bull Hausser and Tupper LLC
  78. Bundesamt für Strahlenschutz
  79. Canadian National (CN)
  80. Coca Cola Company
  81. Copp Clark Ltd.
  82. Crawford and Company Canada Inc
  83. CRDF Global
  84. Dillon Consulting Limited
  85. Dow Chemical Company 
  86. Emdata Co. Ltd. 
  87. Emmons & Olivier Resources Canada Inc. (EOR)
  88. Engineers Canada
  89. ESSA Technologies Ltd. 
  90. Federated Press
  91. FNC Technology Co., Ltd.
  92. Geneva International Airport
  93. Hatch Limited
  94. Helmholtz Zentrum München
  95. Hydro Ottawa
  96. ICF International
  97. Intersol Group Ltd.
  98. Intertek Health Sciences Inc.
  99. IRIS Legal
  100. Japan Nus Company Ltd.
  101. King & Spalding
  102. Lakind Associates LLC
  103. Lansdowne Technologies
  104. Lapointe Engineering Ltd 
  105. Lockheed Martin
  106. Lumina Decision Systems
  107. Manulife Financial Real Estate
  108. MARS Foods (China) Co. Ltd.
  109. Matrix Solutions Inc
  110. McCague Borlack LLP
  111. McCarthy Tetrault LLP
  112. Meat and Livestock Australia
  113. MITACS 
  114. Mondelēz International
  115. Morrison Hershfield
  116. Moto Internationale
  117. Motosport Plus
  118. Nodelcorp Consulting Inc
  119. NORR
  120. Novel Futures Corporation
  121. NTNU Regnskapsseksjonen
  122. Phillips & Paolicelli LLP (P2Law)
  123. Price Waterhouse Coopers (PWC) 
  124. Querencia Partners Ltd.
  125. R.V. Anderson Associates Ltd
  126. Restaino Law Firm
  127. Rio Tinto
  128. RWDI Air Inc 
  129. Science Applications International Corporation (SAIC) 
  130. Social and Scientific Systems, Inc
  131. Stantec Consulting Ltd. 
  132. Summit Toxicology LLP
  133. TetraTech Inc.
  134. Toronto Hydro-Electric System Limited
  135. Torys LLP
  136. TriEdge & Associates
  137. Unilever 
  138. Versar, Inc.
  139. WSP

 

Academia

Universities and research institutes that RSI has served or partnered with:
 

  1. Carleton University
  2. Dankook University
  3. Ecole Polytechnique de Montreal  
  4. George Washington University 
  5. Harvard University  
  6. International Prevention Research Institute (IPRI)
  7. International University of Health and Welfare, Tochigi, Japan
  8. Johns Hopkins School of Medicine
  9. Keio University 
  10. Massachusetts Institute of Technology (MIT)
  11. McGill University
  12. McLaughlin Centre for Population Health
  13. Medizinische Hochschule Brandenburg Theodor Fontane
  14. Nagasaki University
  15. Oak Ridge Associated Universities 
  16. Ottawa Hospital Research Institute 
  17. Rutgers University
  18. Trent University 
  19. Universitätsmedizin Greifswald
  20. Université de Montréal 
  21. University of Alberta
  22. University of Bergen
  23. University of Calgary
  24. University of California, Berkeley
  25. University of California, San Francisco
  26. University of Guelph
  27. University of Korea 
  28. University of Manchester
  29. University of Maryland
  30. University of Melbourne
  31. University of Minnesota
  32. University of Ottawa 
  33. University of Pennsylvania
  34. University of Prince Edward Island
  35. University of Southern California
  36. University of Tasmania 
  37. University of Toronto
  38. University of Washington
  39. University of Windsor
  40. Vanderbilt University
  41. Yukon College

The list of organizations, companies, and governments above in no way denotes or implies support or endorsement by these entities. The list is intended as an indication of the breadth of work led and undertaken by Risk Sciences International staff.

During these unique times during which physical distancing is affecting all aspects of society and our economy, RSI is well prepared. Since its inception, the company has been equipped and trained to deliver results remotely. We use virtual meeting applications extensively, as well as virtual training and webinar software. The nature of risk management is such that all RSI staff have always been a moment's notice away from intervening in urgent matters.

Important: Our sincere thanks go out to all first responders worldwide who have so bravely helped us all to face this unique challenge.

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Head Office

Risk Sciences International

700-251 Laurier Avenue W.

Ottawa, ON K1P 5J6

Canada

Connect

Telephone +1-613-260-1424
Fax +1-613-260-1443
Email Please use this contact form
Office: Monday to Friday
9:00 AM - 6:00 PM EST
Client emergencies
24 / 7 / 365

Secondary Offices

Washington, DC, USA | Hilton Head, SC, USA