The Center for Alternatives to Animal Testing and the Animal-Free Safety Assessment recently held their annual meeting on advancing toxicity testing in the 21st century (TT21C). This informal event provided brief updates on cutting edge approaches in toxicology that have accrued since the publication of the 2007 U.S. National Research Council report on Toxicity Testing in the 21st Century: A Vision and a Strategy.
The meeting is part of an annual series of events that, to date, have been held as satellite meetings of the Society of Toxicology (SOT) conventions. This year, however, with the SOT convention held virtually, it was decided to hold the TT21C meeting virtually as well.
Martin Stephens (Johns Hopkins University), who served on the NRC committee along with Daniel Krewski, welcomed the attendees, followed by brief informal updates as follows:
• ToxCast – Maureen Gwinn (EPA)
• Tox21 – Anton Simeonov (NCATS)
• Organ-on-a-chip & Predictive Toxicology Roadmap – Suzanne Fitzpatrick (FDA)
• Progress in implementing NAMs under TSCA – Louis (Gino) Scarano (EPA)
• ICCVAM/NICEATM – Nicole Kleinstreuer (NICEATM)
• EU-ToxRisk – Bob van de Water (Leiden University)
• AI, iPSC and MPS Projects for Systemic Toxicity – Hajime Kojima (JaCVAM)
• CAAT Activities – Thomas Hartung (Johns Hopkins)
• Evidence-Based Toxicology Collaboration – Katya Tsaioun (Johns Hopkins)
• Animal-Free Safety Assessment Collaboration – Kate Willett (HSI)
• Commentary – Daniel Krewski (U. Ottawa/RSI)
The full meeting (2h34) is available on YouTube and embedded here.